QuickView for Slc26a3 (gene)

Gene Symbol:

SLC26A3 Homo sapiens

Full name:

solute carrier family 26 member 3

Synonyms:

CLD, DRA, chloride anion exchanger, down-regulated in adenoma protein, solute carrier family 26 (anion exchanger), member 3

Genomic Location:

Chr 7: 107193153-107230873

Description:

The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride abso...

View Full Description

The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

STAT4_01 ,  HNF1_01 ,  DR3_Q4 ,  HNF1_C ,  CTTTGA_LEF1_Q2 ,  COUP_01 ,  TGACCTY_ERR1_Q2 ,  HNF4_01 ,  TGCTGAY_UNKNOWN ,  ATGTTTC_MIR494 ,  YCATTAA_UNKNOWN ,  GFI1_01 ,  CART1_01 ,  STAT5A_04 ,  COUP_DR1_Q6 ,  AACTTT_UNKNOWN

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-494

Cytogenetic Map:

7q22.3-q31.1

search → result