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QuickView for Sohlh1 (gene)


Gene Symbol:
SOHLH1 Homo sapiens Homo sapiens
Full name:
spermatogenesis and oogenesis specific basic helix-loop-helix 1
Synonyms:
C9orf157, NOHLH, ODG5, SPATA27, TEB2, bA100C15.3, bHLHe80, spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1, newborn ovary helix loop helix, spermatogenesis associated 27
Genomic Location:
Chr 9: 137725074-137731195
Description:
This gene encodes one of testis-specific transcription factors which are essential for spermatogenesis, oogenesis and folliculogenesis. This gene is located on chromosome 9. Mutations in this gene are associated with nonobstructive azoospermia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 9
9q34.3





GO Molecular Function

RNA polymerase II transcription factor activity, sequence-specific DNA binding | identical protein binding | protein heterodimerization activity | protein binding | protein homodimerization activity | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | protein dimerization activity

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | developmental process involved in reproduction | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cell differentiation | male gamete generation | positive regulation of cellular biosynthetic process | cellular process | multicellular organismal reproductive process | positive regulation of nitrogen compound metabolic process | gamete generation | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | female gamete generation | germ cell development | cellular nitrogen compound biosynthetic process | reproduction | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | reproductive process | multicellular organism development | oocyte differentiation | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | oogenesis | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | multicellular organism reproduction | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cell development | cellular macromolecule biosynthetic process | developmental process | spermatogenesis | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | sexual reproduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular