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QuickView for TAF4b (gene)


Gene Symbol:
TAF4B Homo sapiens Homo sapiens
Full name:
TATA-box binding protein associated factor 4b
Synonyms:
SPGF13, TAF2C2, TAFII105, transcription initiation factor TFIID subunit 4B, TAF(II)105, TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa, TATA box binding protein (TBP)-associated factor 4B, TATA box binding protein (TBP)-associated factor, RNA polymerase II, C2, 105kD, transcription initiation factor TFIID 105 kDa subunit
Genomic Location:
Chr 18: 22060407-22225647
Description:
TATA binding protein (TBP) and TBP-associated factors (TAFs) participate in the formation of the TFIID protein complex, which is involved in initiation of transcription of genes by RNA polymerase II. This gene encodes a cell type-specific TAF that may be responsible for mediating transcription by a subset of activators in B cells. Three transcript ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 18
18q11.2





GO Molecular Function

NF-kappaB binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nucleic acid binding | DNA binding | protein heterodimerization activity | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly | organic cyclic compound binding | protein binding | DNA-binding transcription factor activity | transcription factor binding | protein dimerization activity | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | positive regulation of macromolecule biosynthetic process | developmental process involved in reproduction | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cell differentiation | male gamete generation | positive regulation of cellular biosynthetic process | cellular process | multicellular organismal reproductive process | positive regulation of nitrogen compound metabolic process | gamete generation | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | female gamete generation | germ cell development | cellular nitrogen compound biosynthetic process | protein-DNA complex assembly | reproduction | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | regulation of gene expression | regulation of signal transduction by p53 class mediator | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | oogenesis | biosynthetic process | aromatic compound biosynthetic process | cellular protein-containing complex assembly | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly | DNA-templated transcriptional preinitiation complex assembly | RNA polymerase II transcriptional preinitiation complex assembly | regulation of cellular metabolic process | regulation of RNA metabolic process | multicellular organism reproduction | protein-containing complex assembly | DNA-binding transcription factor activity | regulation of intracellular signal transduction | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | regulation of cell communication | regulation of transcription, DNA-templated | cell development | cellular macromolecule biosynthetic process | developmental process | spermatogenesis | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | positive regulation of metabolic process | cellular metabolic process | sexual reproduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | catalytic complex | RNA polymerase II transcription factor complex | fibrillar center | cell | nuclear lumen | transcription factor complex | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | transferase complex | membrane-bounded organelle | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | transcription factor TFIID complex | RNA polymerase complex | membrane-enclosed lumen | intracellular | RNA polymerase II, holoenzyme