QuickView for TAF8 (gene)

Gene Symbol:

TAF8 Homo sapiens

Full name:

TATA-box binding protein associated factor 8

Synonyms:

II, TAF, TAFII-43, TAFII43, TBN, transcription initiation factor TFIID subunit 8, TAF(II)43, TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa, TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa, TBP-associated factor 43 kDa, TBP-associated factor 8, TBP-associated factor TAFII43, TBP-associated factor, RNA polymerase II, 43 kD, hTAFII43, protein taube nuss, taube nuss homolog, transcription initiation factor TFIID 43 kDa subunit

Genomic Location:

Chr 6: 42126229-42156622

Description:

This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The prot...

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This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  RTAAACA_FREAC2_01 ,  ETS_Q4 ,  MZF1_01 ,  RYTTCCTG_ETS2_B ,  NGFIC_01 ,  NFY_C ,  HFH1_01 ,  TEL2_Q6 ,  GGGCGGR_SP1_Q6 ,  ACTAYRNNNCCCR_UNKNOWN ,  MGGAAGTG_GABP_B ,  CTTTGT_LEF1_Q2 ,  ETS1_B

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Cytogenetic Map:

6p21.1

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