QuickView for TAL1 (gene)
- Gene Symbol:
- TAL1
Homo sapiens - Full name:
- TAL bHLH transcription factor 1, erythroid differentiation factor
- Synonyms:
- SCL, TCL5, bHLHa17, tal-1, T-cell acute lymphocytic leukemia protein 1, T-cell acute lymphocytic leukemia 1, T-cell leukemia/lymphoma protein 5, class A basic helix-loop-helix protein 17, stem cell protein, tal-1 product
- Genomic Location:
- Chr 1: 47454551-47468030
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
1p33
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | enhancer binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | chromatin binding | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | E-box binding | DNA binding | sequence-specific double-stranded DNA binding | protein heterodimerization activity | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II transcription factor binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | histone deacetylase binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | positive regulation of erythrocyte differentiation | cell morphogenesis | positive regulation of macromolecule biosynthetic process | negative regulation of immune system process | positive regulation of cellular component organization | positive regulation of peptidyl-tyrosine phosphorylation | erythrocyte homeostasis | regulation of immune system process | myeloid cell differentiation | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | bone development | cell differentiation | positive regulation of signaling receptor activity | nervous system development | regulation of hematopoietic progenitor cell differentiation | neurogenesis | positive regulation of phosphate metabolic process | erythrocyte maturation | regulation of organelle organization | generation of neurons | blood vessel morphogenesis | positive regulation of cellular biosynthetic process | cellular process | cell maturation | mesoderm morphogenesis | central nervous system neuron differentiation | mesoderm development | immune system development | negative regulation of nucleic acid-templated transcription | positive regulation of protein kinase activity | dorsal spinal cord development | regulation of cell cycle | positive regulation of catalytic activity | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | myeloid cell development | positive regulation of cell division | negative regulation of cellular metabolic process | tissue development | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | hemangioblast cell differentiation | regulation of cellular process | regulation of metabolic process | gliogenesis | spinal cord association neuron differentiation | regulation of protein complex assembly | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | basophil differentiation | cellular component organization | regulation of cell division | negative regulation of erythrocyte differentiation | vasculature development | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | mesoderm formation | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | hematopoietic progenitor cell differentiation | cardiovascular system development | cellular nitrogen compound metabolic process | regulation of stem cell population maintenance | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | platelet formation | hemopoiesis | negative regulation of hemopoiesis | cellular biosynthetic process | embryo development | blood vessel development | myeloid cell homeostasis | regulation of nucleic acid-templated transcription | leukocyte differentiation | regulation of protein tyrosine kinase activity | system development | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | multicellular organism development | regulation of catalytic activity | embryonic hemopoiesis | regulation of phosphorylation | positive regulation of chromosome organization | positive regulation of cell cycle | regulation of hematopoietic stem cell differentiation | positive regulation of mitotic cell cycle | regulation of gene expression | platelet morphogenesis | myeloid leukocyte differentiation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | negative regulation of myeloid cell differentiation | regulation of nitrogen compound metabolic process | definitive hemopoiesis | positive regulation of protein complex assembly | regulation of chromatin assembly or disassembly | regulation of transcription by RNA polymerase II | primitive hemopoiesis | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | homeostasis of number of cells | stem cell differentiation | granulocyte differentiation | biosynthetic process | locomotory behavior | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | glial cell differentiation | angiogenesis | megakaryocyte differentiation | cell morphogenesis involved in differentiation | erythrocyte development | astrocyte fate commitment | regulation of cellular metabolic process | regulation of protein kinase activity | astrocyte differentiation | regulation of protein metabolic process | homeostatic process | regulation of protein phosphorylation | regulation of RNA metabolic process | regulation of stem cell differentiation | embryonic morphogenesis | regulation of mitotic cell cycle | positive regulation of molecular function | neuron differentiation | regulation of signaling receptor activity | DNA-binding transcription factor activity | positive regulation of protein modification process | tissue morphogenesis | regulation of hemopoiesis | regulation of kinase activity | anatomical structure development | metabolic process | cell fate commitment | regulation of RNA biosynthetic process | developmental maturation | negative regulation of transcription, DNA-templated | embryonic organ development | regulation of mast cell differentiation | regulation of erythrocyte differentiation | behavior | nucleobase-containing compound metabolic process | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | positive regulation of kinase activity | regulation of phosphate metabolic process | regulation of chromosome organization | transcription, DNA-templated | anatomical structure formation involved in morphogenesis | cell differentiation in spinal cord | regulation of cell communication | regulation of transcription, DNA-templated | glial cell fate commitment | cell development | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | hematopoietic stem cell differentiation | regulation of developmental process | developmental process | erythrocyte differentiation | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | formation of primary germ layer | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | central nervous system development | mesodermal cell differentiation | spinal cord development | positive regulation of metabolic process | positive regulation of chromatin assembly or disassembly | skeletal system development | gastrulation | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | megakaryocyte development | circulatory system development | negative regulation of cell differentiation | regulation of cellular component organization | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of chromatin organization | regulation of phosphorus metabolic process
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | transcription factor complex | intracellular organelle | protein-containing complex | histone deacetylase complex | nucleoplasm | chromatin | nuclear chromosome | Lsd1/2 complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | intracellular
