QuickView for TEP1 (gene)
- Gene Symbol:
- TEP1
Homo sapiens - Full name:
- telomerase associated protein 1
- Synonyms:
- TLP1, TP1, TROVE1, VAULT2, p240, telomerase protein component 1, TROVE domain family, member 1, p80 telomerase homolog, telomerase protein 1
- Genomic Location:
- Chr 14: 19905766-19951420
- Description:
-
This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
14q11.2
GO Molecular Function
telomerase RNA binding | enzyme binding | nucleic acid binding | ribonucleotide binding | nucleotide binding | telomerase activity | carbohydrate derivative binding | DNA polymerase activity | nucleotidyltransferase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | p53 binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | RNA-directed DNA polymerase activity | drug binding | heterocyclic compound binding | small molecule binding | RNA binding
GO Biological Process
telomere maintenance | cellular process | anatomical structure homeostasis | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | telomerase activity | cellular nitrogen compound biosynthetic process | DNA polymerase activity | cellular nitrogen compound metabolic process | telomere organization | cellular biosynthetic process | DNA recombination | nitrogen compound metabolic process | DNA biosynthetic process | RNA-dependent DNA biosynthetic process | biosynthetic process | aromatic compound biosynthetic process | homeostatic process | DNA metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | mitotic recombination | telomere maintenance via recombination | cellular macromolecule biosynthetic process | RNA-directed DNA polymerase activity | organelle organization | heterocycle metabolic process | chromosome organization | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | ribonucleoprotein complex | chromosome, telomeric region | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear matrix | telomerase holoenzyme complex | intracellular | nuclear periphery
