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QuickView for TET3 (gene)


Gene Symbol:
TET3 Homo sapiens Homo sapiens
Full name:
tet methylcytosine dioxygenase 3
Synonyms:
hCG_40738, methylcytosine dioxygenase TET3, probable methylcytosine dioxygenase TET3, putative methylcytosine dioxygenase, tet oncogene family member 3
Genomic Location:
Chr 2: 74126958-74188811
Description:
Members of the ten-eleven translocation (TET) gene family, including TET3, play a role in the DNA methylation process (Langemeijer et al., 2009 [PubMed 19923888]).
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Cytogenetic Map:
chr 2
2p13.1





GO Molecular Function

RNA polymerase II transcription factor activity, sequence-specific DNA binding | cation binding | nucleic acid binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | DNA binding | ion binding | organic cyclic compound binding | protein binding | DNA-binding transcription factor activity | dioxygenase activity | methylcytosine dioxygenase activity | transition metal ion binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity

GO Biological Process

positive regulation of macromolecule biosynthetic process | peptidyl-amino acid modification | DNA modification | RNA polymerase II transcription factor activity, sequence-specific DNA binding | histone modification | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | chromatin organization | DNA methylation involved in embryo development | DNA demethylation of male pronucleus | positive regulation of nitrogen compound metabolic process | glycoprotein biosynthetic process | regulation of cellular process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | histone H3-K4 trimethylation | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | 5-methylcytosine metabolic process | histone H3-K4 methylation | cellular nitrogen compound metabolic process | peptidyl-lysine trimethylation | carbohydrate derivative biosynthetic process | positive regulation of RNA biosynthetic process | protein modification process | macromolecule glycosylation | cellular biosynthetic process | embryo development | macromolecule modification | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | multicellular organism development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | histone methylation | regulation of gene expression | methylation | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | DNA methylation | biosynthetic process | DNA demethylation | regulation of cellular metabolic process | aromatic compound catabolic process | regulation of RNA metabolic process | protein metabolic process | DNA-binding transcription factor activity | peptidyl-lysine methylation | DNA metabolic process | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | oxidation-reduction process | peptidyl-lysine modification | nucleobase-containing compound metabolic process | organic substance metabolic process | histone lysine methylation | dioxygenase activity | protein O-linked glycosylation | methylcytosine dioxygenase activity | organonitrogen compound catabolic process | covalent chromatin modification | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | protein methylation | 5-methylcytosine catabolic process | developmental process | organelle organization | cellular protein modification process | carbohydrate derivative metabolic process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | demethylation | protein glycosylation | glycosylation | positive regulation of metabolic process | chromosome organization | cellular metabolic process | oxidoreductase activity | glycoprotein metabolic process | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | pronucleus | membrane-bounded organelle | nucleus | organelle | female pronucleus | male pronucleus | intracellular