QuickView for TEX15 (gene)

Gene Symbol:

TEX15 Homo sapiens

Full name:

testis expressed 15, meiosis and synapsis associated

Synonyms:

CT42, testis-expressed protein 15, testis-expressed sequence 15 protein, cancer/testis antigen 42

Genomic Location:

Chr 8: 30808602-30826075

Description:

This gene encodes a protein that is required for DNA double-strand break repair, chromosome synapsis, and meiotic recombination in spermatocytes. Male mice with a knockout of the orthologous gene are viable but sterile. Loss-of-function mutations in the orthologous mouse gene cause early meiotic arrest in spermatocytes, before the mid-pachytene sta...

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This gene encodes a protein that is required for DNA double-strand break repair, chromosome synapsis, and meiotic recombination in spermatocytes. Male mice with a knockout of the orthologous gene are viable but sterile. Loss-of-function mutations in the orthologous mouse gene cause early meiotic arrest in spermatocytes, before the mid-pachytene stage. Naturally occurring mutations in this gene are associated with nonobstructive azoospermia.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  TTANTCA_UNKNOWN ,  AFP1_Q6 ,  TCCATTKW_UNKNOWN

Cytogenetic Map:

8p12

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