QuickView for THEM4;jsessionid=99C56978057B3C343588421C6EFC8A8A (gene)

Gene Symbol:

THEM4 Homo sapiens

Full name:

thioesterase superfamily member 4

Synonyms:

CTMP, acyl-coenzyme A thioesterase THEM4, C-terminal modulator protein, acyl-CoA thioesterase THEM4, carboxyl-terminal modulator protein

Genomic Location:

Chr 1: 150112684-150148737

Description:

Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphoryl...

View Full Description

Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GTGCCAT_MIR183

Cytogenetic Map:

1q21.3

search → result