QuickView for TNRC11L (gene)
- Gene Symbol:
- MED12L
Homo sapiens - Full name:
- mediator complex subunit 12 like
- Synonyms:
- NOPAR, TNRC11L, TRALP, TRALPUSH, mediator of RNA polymerase II transcription subunit 12-like protein, mediator of RNA polymerase II transcription, subunit 12 homolog-like, no opposite paired repeat protein, thyroid hormone receptor-associated-like protein, trinucleotide repeat-containing gene 11 protein-like
- Genomic Location:
- Chr 3: 152287366-152634500
- Description:
-
The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Gallus gallus , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-101 , Predicted Gene Targets for miR-130 , Predicted Gene Targets for miR-133 , Predicted Gene Targets for miR-142-5p , Predicted Gene Targets for miR-144 , Predicted Gene Targets for miR-148 , Predicted Gene Targets for miR-19 , Predicted Gene Targets for miR-20 , Predicted Gene Targets for miR-218 , Predicted Gene Targets for miR-28
- Cytogenetic Map:
-
3q25.1
GO Molecular Function
beta-catenin binding | transcription coactivator activity | protein binding | transcription coregulator activity
GO Biological Process
RNA metabolic process | positive regulation of macromolecule biosynthetic process | positive regulation of cellular biosynthetic process | cellular process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | transcription coactivator activity | regulation of RNA metabolic process | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | intracellular organelle | protein-containing complex | nucleoplasm | mediator complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
