QuickView for TRDMT1 (gene)

Gene Symbol:

TRDMT1 Homo sapiens

Full name:

tRNA aspartic acid methyltransferase 1

Synonyms:

DMNT2, DNMT2, MHSAIIP, PUMET, RNMT1, tRNA (cytosine(38)-C(5))-methyltransferase, DNA (cytosine-5)-methyltransferase-like protein 2, DNA MTase homolog HsaIIP, DNA cytosine-5 methyltransferase 2, DNA methyltransferase-2, tRNA (cytosine-5-)-methyltransferase

Genomic Location:

Chr 10: 17224988-17283687

Description:

This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conse...

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This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Gallus gallus ,  Danio rerio ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  GTTGNYNNRGNAAC_UNKNOWN

Cytogenetic Map:

10p13

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