QuickView for TRG-9 (gene)

Gene Symbol:

SNX2 Homo sapiens

Full name:

sorting nexin 2

Synonyms:

TRG-9, sorting nexin-2, CTB-36H16.2, transformation-related gene 9 protein

Genomic Location:

Chr 5: 122138649-122193702

Description:

This gene belongs to the sorting nexin family whose members contain the phosphoinositide-binding phox (PX) domain. The encoded protein is a component of the retromer complex which plays a role in protein sorting in the endocytic pathway. This protein may form oligomeric complexes with other family members. Alternate splicing results in multiple tra...

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This gene belongs to the sorting nexin family whose members contain the phosphoinositide-binding phox (PX) domain. The encoded protein is a component of the retromer complex which plays a role in protein sorting in the endocytic pathway. This protein may form oligomeric complexes with other family members. Alternate splicing results in multiple transcript variants of this gene. Pseudogenes associated with this gene are located on chromosomes 1 and 7.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  USF_Q6 ,  TCANNTGAY_SREBP1_01 ,  ARNT_01 ,  NFAT_Q6 ,  CACGTG_MYC_Q2 ,  ATTACAT_MIR3803P ,  ARNT_02 ,  TTGCACT_MIR130A_MIR301_MIR130B ,  AR_Q6 ,  SREBP1_01 ,  ACATTCC_MIR1_MIR206 ,  GGGYGTGNY_UNKNOWN ,  SP1_Q4_01 ,  SP1_Q6 ,  AAACCAC_MIR140 ,  ELF1_Q6 ,  SP1_Q2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-208 ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-299 ,  Predicted Gene Targets for miR-140 ,  Predicted Gene Targets for miR-410 ,  Predicted Gene Targets for miR-499

Cytogenetic Map:

5q23.2

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