QuickView for Tle1 (gene)
- Gene Symbol:
- TLE1
Homo sapiens - Full name:
- transducin like enhancer of split 1
- Synonyms:
- ESG, ESG1, GRG1, transducin-like enhancer protein 1, enhancer of split groucho-like protein 1, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
- Genomic Location:
- Chr 9: 83388418-83493416
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
9q21.32
GO Molecular Function
repressing transcription factor binding | transcription corepressor activity | identical protein binding | protein binding | transcription factor binding | transcription coregulator activity
GO Biological Process
RNA metabolic process | regulation of programmed cell death | negative regulation of cellular process | negative regulation of RNA biosynthetic process | cellular process | negative regulation of signaling | negative regulation of anoikis | negative regulation of nucleic acid-templated transcription | negative regulation of apoptotic process | regulation of canonical Wnt signaling pathway | negative regulation of cellular metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | cellular nitrogen compound biosynthetic process | beta-catenin-TCF complex assembly | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular component assembly | regulation of anoikis | cellular biosynthetic process | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | regulation of signal transduction | Wnt signaling pathway | multicellular organism development | regulation of gene expression | animal organ morphogenesis | regulation of nitrogen compound metabolic process | transcription corepressor activity | biosynthetic process | aromatic compound biosynthetic process | cell communication | regulation of cellular metabolic process | regulation of RNA metabolic process | protein-containing complex assembly | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | negative regulation of I-kappaB kinase/NF-kappaB signaling | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | regulation of Wnt signaling pathway | transcription, DNA-templated | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | developmental process | negative regulation of canonical Wnt signaling pathway | transcription coregulator activity | heterocycle metabolic process | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | cellular metabolic process | regulation of cell death | negative regulation of cell death | regulation of I-kappaB kinase/NF-kappaB signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
nuclear transcription factor complex | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | beta-catenin-TCF complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
