QuickView for Tnnc2 (gene)
- Gene Symbol:
- TNNC2
Homo sapiens - Full name:
- troponin C2, fast skeletal type
- Synonyms:
- troponin C, skeletal muscle, troponin C type 2 (fast)
- Genomic Location:
- Chr 20: 43885260-43889360
- Description:
-
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this g...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Danio rerio , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
20q13.12
GO Molecular Function
actin binding | actin filament binding | cation binding | protein-containing complex binding | cytoskeletal protein binding | calcium-dependent protein binding | ion binding | protein binding | calcium ion binding | metal ion binding
GO Biological Process
multicellular organismal movement | regulation of muscle system process | actin filament-based process | cellular process | musculoskeletal movement | actin filament-based movement | actin-mediated cell contraction | muscle contraction | actin-myosin filament sliding | regulation of muscle contraction | muscle filament sliding | striated muscle contraction | skeletal muscle contraction | muscle system process | multicellular organismal process
GO Cellular Component
supramolecular fiber | sarcomere | cell | myofibril | cytoplasm | striated muscle thin filament | intracellular organelle | actin cytoskeleton | contractile fiber | protein-containing complex | troponin complex | organelle | cytosol | cytoskeleton | intracellular | supramolecular complex
