QuickView for Topbp1 (gene)

Gene Symbol:

TOPBP1 Homo sapiens

Full name:

DNA topoisomerase II binding protein 1

Synonyms:

TOP2BP1, DNA topoisomerase 2-binding protein 1, DNA topoisomerase II-beta-binding protein 1, topoisomerase (DNA) II binding protein 1

Genomic Location:

Chr 3: 134802177-134863380

Description:

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

OCT1_05 ,  OCT1_04 ,  E2F1_Q4_01 ,  E2F4DP1_01 ,  E2F_Q6_01 ,  E2F_01 ,  GGGAGGRR_MAZ_Q6 ,  E2F_Q6 ,  E2F1_Q6_01 ,  TATA_C ,  E2F_Q4 ,  E2F1DP2_01 ,  YTTCCNNNGGAMR_UNKNOWN ,  E2F1_Q3_01 ,  CTTTAAR_UNKNOWN ,  E2F_03 ,  E2F1DP1_01 ,  E2F_Q4_01 ,  TTGCCAA_MIR182 ,  E2F1DP1RB_01 ,  E2F_02 ,  E2F1_Q3 ,  E2F4DP2_01 ,  KTGGYRSGAA_UNKNOWN ,  MMEF2_Q6 ,  E2F_Q3 ,  E2F_Q3_01 ,  E2F1_Q6 ,  SGCGSSAAA_E2F1DP2_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-182

Cytogenetic Map:

3q22.1

search → result