QuickView for USP35 (gene)

Gene Symbol:

USP35 Homo sapiens

Full name:

ubiquitin specific peptidase 35

Synonyms:

ubiquitin carboxyl-terminal hydrolase 35, deubiquitinating enzyme 35, ubiquitin specific protease 35, ubiquitin thioesterase 35, ubiquitin thiolesterase 35, ubiquitin-specific-processing protease 35

Genomic Location:

Chr 11: 77577606-77603401

Description:

This gene encodes a member of the peptidase C19 family of ubiquitin-specific proteases. These deubiquitinating enzymes (DUBs) catalyze the removal of ubiquitin proteins from other proteins. The encoded protein associates with polarized mitochondria and has been shown to inhibit NF-kappa B activation and delay PARK2-mediated degradation of mitochond...

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This gene encodes a member of the peptidase C19 family of ubiquitin-specific proteases. These deubiquitinating enzymes (DUBs) catalyze the removal of ubiquitin proteins from other proteins. The encoded protein associates with polarized mitochondria and has been shown to inhibit NF-kappa B activation and delay PARK2-mediated degradation of mitochondria. Expression of this gene is upregulated by the let-7a microRNA and reduced expression has been observed in human tumor tissues.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Cytogenetic Map:

11q14.1

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