QuickView for VPS41 (gene)

Gene Symbol:

VPS41 Homo sapiens

Full name:

VPS41, HOPS complex subunit

Synonyms:

HVPS41, HVSP41, hVps41p, vacuolar protein sorting-associated protein 41 homolog, S53, vacuolar assembly protein 41, vacuolar protein sorting 41 homolog

Genomic Location:

Chr 7: 38730068-38915325

Description:

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Dros...

View Full Description

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

STAT1_02 ,  TCANNTGAY_SREBP1_01 ,  STAT1_03 ,  WTGAAAT_UNKNOWN ,  TNCATNTCCYR_UNKNOWN ,  AACYNNNNTTCCS_UNKNOWN ,  YKACATTT_UNKNOWN ,  ACTAYRNNNCCCR_UNKNOWN ,  RACTNNRTTTNC_UNKNOWN

Cytogenetic Map:

7p14.1

search → result