QuickView for angptl3 (gene)

Gene Symbol:

ANGPTL3 Homo sapiens

Full name:

angiopoietin like 3

Synonyms:

ANG-5, ANGPT5, ANL3, FHBL2, angiopoietin-related protein 3, angiopoietin 5

Genomic Location:

Chr 1: 62835775-62843768

Description:

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal cha...

View Full Description

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YATTNATC_UNKNOWN ,  HNF1_Q6

Cytogenetic Map:

1p31.3

search → result