Name: | Aryl Hydrocarbon Hydroxylases |
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Description: | A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides. |
Synonyms: |
Monooxygenases, Microsomal; Microsomal Monooxygenases; Hydroxylases, Aryl Hydrocarbon
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