Name: | Citrulline |
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PubChem Compound ID: | 637599 |
Molecular formula: | C6H13N3O3 |
Molecular weight: | 175.186 g/mol |
Synonyms: |
372-75-8; N~5~-(aminocarbonyl)ornithine; ornithine, N~5~-(aminocarbonyl)-; CITRULLINE (L); InChI=1/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12
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Name: | Citrulline |
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Name (isomeric): | DB00155 |
Drug Type: | small molecule |
Synonyms: |
N5-carbamylornithine; N5-Carbamoyl-L-ornithine; Sitrulline; N5-carbamoylornithine; N5-(Aminocarbonyl)ornithine; delta-Ureidonorvaline; Citrulline; 2-Amino-5-uredovaleric acid
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Category: | Micronutrient, Dietary supplement, Non-Essential Amino Acids |
CAS number: | 372-75-8 |
Indication: | Used for nutritional supplementation, also for treating dietary shortage or imbalance. |
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Pharmacology: |
A non-essential amino acid and a precursor of arginine. Citrulline supplements have been claimed to promote energy levels, stimulate the immune system and help detoxify ammonia (a cell toxin). L-citrulline is made from L-ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from L-arginine as a by-...
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Mechanism of Action: |
L-citrulline is converted to L-arginine by argininosuccinate synthase. L-arginine is in turn responsible for citrulline's therapeutic affects. Many of L-arginine's activities, including its possible anti-atherogenic actions, may be accounted for by its role as the precursor to nitric oxide or NO. NO is produced by all tissues of the body and plays ...
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Affected organisms: | Humans and other mammals |