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PubChem
| Name: | Creatine |
|---|---|
| PubChem Compound ID: | 586 |
| Description: | An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine. |
| Molecular formula: | C4H9N3O2 |
| Molecular weight: | 131.133 g/mol |
| Synonyms: |
AI3-15320; CHEBI:16919; N-Amidinosarcosine; Creatine, hydrate; Creatin; Creatine; Creatine (8CI); Krebiozon; Methylglycocyamine; methylguanidinoacetic acid.
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DrugBank
Identification
| Name: | Creatine |
|---|---|
| Name (isomeric): | DB00148 |
| Drug Type: | small molecule |
| Description: | An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine. |
| Synonyms: |
Methylguanidoacetic acid; Creatine (8CI); N-Amidinosarcosine; N-Methyl-N-guanylglycine; Creatine, hydrate; (alpha-Methylguanido)acetic acid
|
| Brand: | Krebiozon, Kreatin, Pyrolysate, Cosmocair C 100, Creatin, Phosphagen |
| Category: | Micronutrient, Dietary supplement |
| CAS number: | 57-00-1 |
Pharmacology
| Indication: | For nutritional supplementation, also for treating dietary shortage or imbalance |
|---|---|
| Pharmacology: |
Creatine is a essential, non-proteinaceous amino acid found in all animals and, in some plants. Creatine is synthesized in the kidney, liver and pancreas from L-arginine, glycine and L-methionine. Following its biosynthesis, creatine is transported to the skeletal muscle, heart, brain and other tissues. Most of the creatine is metabolized in these ...
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| Mechanism of Action: |
In the muscles, a fraction of the total creatine binds to phosphate - forming creatine phosphate. The reaction is catalysed by creatine kinase, and the result is phosphocreatine (PCr). Phosphocreatine binds with adenosine diphosphate to convert it back to ATP (adenosine triphosphate), an important cellular energy source for short term ATP needs pri...
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| Half Life: | 3 hours |
| Affected organisms: | Humans and other mammals |
Targets
Transporters
