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QuickView for isoflurophate (compound)
PubChem
| Name: | Isoflurophate |
|---|---|
| PubChem Compound ID: | 5936 |
| Description: | A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM. |
| Molecular formula: | C6H14FO3P |
| Molecular weight: | 184.146 g/mol |
| Synonyms: |
4-01-00-01480 (Beilstein Handbook Reference); Isoflurophosphate; Fluostigmine; DIISOPROPYL FLUOROPHOSPHATE; Diflurophate; RCRA waste number P043; Diisopropyl fluorophosphonate; O,O-Diisopropyl fluorophosphate; RCRA waste no. P043; Isoflurophate (USP).
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DrugBank
Identification
| Name: | Isoflurophate |
|---|---|
| Name (isomeric): | DB00677 |
| Drug Type: | small molecule |
| Description: | A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM. |
| Synonyms: |
Diflurophate; Diisopropoxyphosphoryl Fluoride; Diflupyl; DFP
|
| Brand: | Fluorodiisopropyl Phosphate, Isofluorophate, Diisopropylfluorfosfat, Isofluorphate, Fluropryl, O,O-Diisopropyl Fluorophosphate, Disiopropyl Fluorophosphonate, Dyflos, Isopropyl Phosphorofluoridate, Diisopropyl Fluoridophosphate, Fluostigmine, Fluoropryl, Diisopropyl Phosphofluoridate, Diisopropyl Fluorophosphonate, Diisopropyl Fluorophosphate, Diisopropyl Phosphorofluoridate, Floropryl, Isopropyl Fluophosphate, PF-3, Neoglaucit, Isoflurophosphate, Humorsol |
| Category: | Cholinesterase Inhibitors, Antiglaucomic Agents, Miotics, Ophthalmics, Protease Inhibitors |
| CAS number: | 55-91-4 |
Pharmacology
| Indication: | For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. |
|---|---|
| Pharmacology: |
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotrop...
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| Mechanism of Action: | The mechanism of isoflurophate's action involves the irreversible inhibition of cholinesterase. |
| Toxicity: | Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth. |
| Affected organisms: | Humans and other mammals |
Targets
Enzymes
