QuickView for noxA (gene)
- Gene Symbol:
- PMAIP1
Homo sapiens - Full name:
- phorbol-12-myristate-13-acetate-induced protein 1
- Synonyms:
- APR, NOXA, phorbol-12-myristate-13-acetate-induced protein 1, PMA-induced protein 1, adult T cell leukemia-derived PMA-responsive, immediate-early-response protein APR, protein Noxa
- Genomic Location:
- Chr 18: 55718172-55722518
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes
- External Links:
- Entrez Gene
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
18q21.32
GO Molecular Function
GO Biological Process
leukocyte homeostasis | response to extracellular stimulus | cellular response to glucose starvation | cellular response to decreased oxygen levels | regulation of cysteine-type endopeptidase activity | response to virus | response to nutrient levels | release of cytochrome c from mitochondria | positive regulation of cellular component organization | mitochondrial outer membrane permeabilization | regulation of cellular localization | intracellular signal transduction | positive regulation of apoptotic process | proteolysis | protein localization to mitochondrion | regulation of localization | regulation of carbohydrate metabolic process | regulation of programmed cell death | regulation of mitochondrial membrane permeability involved in apoptotic process | defense response to other organism | establishment of localization | positive regulation of mitochondrial membrane permeability involved in apoptotic process | regulation of protein localization to membrane | positive regulation of intrinsic apoptotic signaling pathway | defense response | cellular response to extracellular stimulus | reactive oxygen species metabolic process | regulation of protein oligomerization | regulation of organelle organization | membrane organization | negative regulation of mitochondrial membrane potential | cellular process | positive regulation of signal transduction by p53 class mediator | organic substance catabolic process | localization | proteolysis involved in cellular protein catabolic process | regulation of DNA damage response, signal transduction by p53 class mediator | regulation of mitochondrial membrane potential | establishment of protein localization to mitochondrion | macromolecule localization | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | response to hypoxia | positive regulation of release of cytochrome c from mitochondria | cellular response to starvation | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | intrinsic apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | regulation of protein complex assembly | positive regulation of cellular protein metabolic process | cellular component organization | positive regulation of response to DNA damage stimulus | response to stimulus | regulation of cellular protein localization | positive regulation of protein metabolic process | positive regulation of peptidase activity | cellular response to hypoxia | response to stress | regulation of response to endoplasmic reticulum stress | positive regulation of cellular protein localization | positive regulation of cysteine-type endopeptidase activity | response to starvation | programmed cell death | cellular protein catabolic process | cellular localization | positive regulation of proteolysis | proteasomal protein catabolic process | apoptotic mitochondrial changes | mitochondrion organization | positive regulation of membrane permeability | positive regulation of mitochondrion organization | regulation of membrane potential | regulation of cellular response to stress | response to nitrogen compound | apoptotic process | response to external biotic stimulus | cellular response to nutrient levels | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | regulation of peptidase activity | response to dsRNA | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | cellular response to DNA damage stimulus | regulation of catalytic activity | regulation of intrinsic apoptotic signaling pathway | positive regulation of DNA damage response, signal transduction by p53 class mediator | regulation of extrinsic apoptotic signaling pathway | protein localization to membrane | regulation of mitochondrial membrane permeability | cellular response to stress | protein catabolic process | regulation of signal transduction by p53 class mediator | positive regulation of cellular metabolic process | defense response to virus | mitochondrial transport | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | protein localization to organelle | positive regulation of hydrolase activity | homeostasis of number of cells | regulation of cellular protein metabolic process | protein insertion into membrane | positive regulation of endopeptidase activity | regulation of apoptotic signaling pathway | negative regulation of membrane potential | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of mitochondrion organization | mitochondrial membrane organization | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | mitochondrial outer membrane permeabilization involved in programmed cell death | positive regulation of protein localization to membrane | lymphocyte homeostasis | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | positive regulation of establishment of protein localization | positive regulation of transport | apoptotic signaling pathway | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | positive regulation of molecular function | establishment of protein localization to membrane | protein metabolic process | regulation of establishment of protein localization | response to organic substance | protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | regulation of intracellular signal transduction | cellular macromolecule catabolic process | establishment of protein localization to organelle | regulation of glucose metabolic process | metabolic process | activation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of glucose metabolic process | cellular protein localization | positive regulation of cell death | regulation of response to DNA damage stimulus | positive regulation of mitochondrial membrane permeability | positive regulation of cellular component biogenesis | organic substance metabolic process | cell death | positive regulation of programmed cell death | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | intrinsic apoptotic signaling pathway by p53 class mediator | establishment of protein localization | T cell homeostasis | positive regulation of carbohydrate metabolic process | organonitrogen compound catabolic process | protein insertion into mitochondrial membrane | regulation of cell communication | regulation of membrane permeability | regulation of extrinsic apoptotic signaling pathway via death domain receptors | signaling | response to organic cyclic compound | protein localization | cellular protein metabolic process | regulation of endopeptidase activity | cellular macromolecule localization | response to biotic stimulus | organelle organization | regulation of transport | positive regulation of protein oligomerization | positive regulation of metabolic process | immune system process | cellular metabolic process | regulation of protein localization | regulation of cell death | signal transduction by p53 class mediator | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | positive regulation of response to endoplasmic reticulum stress
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | organelle outer membrane | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | nucleus | organelle | mitochondrial outer membrane | mitochondrial envelope | outer membrane | mitochondrial membrane | cytosol | intracellular | membrane
