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QuickView for nucleostemin (gene)


Gene Symbol:
GNL3 Homo sapiens Homo sapiens
Full name:
G protein nucleolar 3
Synonyms:
C77032, E2IG3, NNP47, NS, guanine nucleotide-binding protein-like 3, E2-induced gene 3 protein, estradiol-induced nucleotide binding protein, guanine nucleotide binding protein-like 3 (nucleolar), novel nucleolar protein 47, nucleolar GTP-binding protein 3, nucleostemin
Genomic Location:
Chr 3: 52694976-52703553
Description:
The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 3
3p21.1


Transcripts Names
NM_014366
NM_206825
NM_206826



GO Molecular Function

guanyl ribonucleotide binding | ribonucleoside binding | nucleic acid binding | ribonucleotide binding | mRNA binding | nucleotide binding | carbohydrate derivative binding | anion binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | GTP binding | mRNA 5'-UTR binding | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | guanyl nucleotide binding | small molecule binding | RNA binding

GO Biological Process

positive regulation of macromolecule biosynthetic process | positive regulation of cellular component organization | regulation of cellular localization | regulation of localization | regulation of organelle organization | positive regulation of cellular biosynthetic process | cellular process | stem cell population maintenance | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | regulation of cellular protein localization | positive regulation of protein metabolic process | positive regulation of cellular protein localization | regulation of cell proliferation | positive regulation of RNA biosynthetic process | regulation of nucleic acid-templated transcription | positive regulation of organelle organization | positive regulation of protein sumoylation | regulation of telomere maintenance | positive regulation of chromosome organization | regulation of gene expression | stem cell division | positive regulation of cellular metabolic process | regulation of pri-miRNA transcription by RNA polymerase II | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | cell proliferation | cell division | regulation of cellular protein metabolic process | positive regulation of pri-miRNA transcription by RNA polymerase II | regulation of protein sumoylation | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of RNA metabolic process | positive regulation of protein modification process | regulation of RNA biosynthetic process | maintenance of cell number | regulation of chromosome organization | positive regulation of protein localization to chromosome, telomeric region | regulation of transcription, DNA-templated | positive regulation of telomere maintenance | positive regulation of DNA metabolic process | developmental process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | regulation of protein localization | regulation of cellular component organization | positive regulation of gene expression | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | intracellular organelle | nuclear body | nucleoplasm | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | membrane-enclosed lumen | intracellular | membrane