QuickView for opisthotonus (gene)
- Gene Symbol:
- Itpr1
Mus musculus - Full name:
- inositol 1,4,5-trisphosphate receptor 1
- Synonyms:
- D6Pas2, Gm10429, IP3R 1, IP3R1, InsP3R, Ip3r, Itpr-1, P400, Pcp-1, Pcp1, insP3R1, opt, wblo, inositol 1,4,5-trisphosphate receptor type 1, IP3 receptor, InsP>3<R type I, Purkinje cell protein 1, inositol 1,4,5-trisphosphate-binding protein P400, opisthotonus, protein PCD-6, type 1 InsP3 receptor, type 1 inositol 1,4,5-trisphosphate receptor
- Genomic Location:
- Chr 6: 108163112-108501103
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , Macaca mulatta , Danio rerio , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-130 , Predicted Gene Targets for miR-143 , Predicted Gene Targets for miR-15 , Predicted Gene Targets for miR-153 , Predicted Gene Targets for miR-19 , Predicted Gene Targets for miR-193 , Predicted Gene Targets for miR-200b , Predicted Gene Targets for miR-204 , Predicted Gene Targets for miR-25 , Predicted Gene Targets for miR-26
GO Molecular Function
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | ligand-gated calcium channel activity | channel regulator activity | cation binding | passive transmembrane transporter activity | enzyme binding | protein-containing complex binding | transmembrane transporter activity | lipid binding | ligand-gated ion channel activity | ion gated channel activity | ion channel inhibitor activity | phospholipid binding | alcohol binding | molecular function regulator | channel inhibitor activity | anion binding | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | identical protein binding | ion transmembrane transporter activity | ion binding | inositol 1,4,5 trisphosphate binding | calcium-release channel activity | protein binding | calcium channel regulator activity | protein phosphatase binding | metal ion transmembrane transporter activity | phosphatidylinositol binding | cation channel activity | calcium ion binding | inorganic cation transmembrane transporter activity | intracellular ligand-gated ion channel activity | calcium channel inhibitor activity | channel activity | calcium channel activity | phosphatase binding | metal ion binding | ion channel activity | protein C-terminus binding | substrate-specific channel activity | small molecule binding
GO Biological Process
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | multicellular organismal movement | response to endoplasmic reticulum stress | intracellular signal transduction | calcium ion transmembrane import into cytosol | cytosolic calcium ion transport | regulation of localization | ligand-gated calcium channel activity | establishment of localization | negative regulation of neuron death | negative regulation of cellular process | fluid transport | cellular chemical homeostasis | inositol phosphate-mediated signaling | regulation of neuron death | response to organophosphorus | cellular process | channel regulator activity | musculoskeletal movement | localization | cellular homeostasis | regulation of calcium-mediated signaling | passive transmembrane transporter activity | negative regulation of signaling | metal ion transport | response to hypoxia | transepithelial transport | establishment of localization in cell | intrinsic apoptotic signaling pathway | regulation of cellular process | regulation of cytosolic calcium ion concentration | transmembrane transporter activity | ligand-gated ion channel activity | cellular response to organonitrogen compound | negative regulation of calcium-mediated signaling | calcium ion homeostasis | calcium ion transport into cytosol | response to stimulus | ion gated channel activity | ion channel inhibitor activity | response to stress | programmed cell death | cellular localization | divalent metal ion transport | cellular response to organic cyclic compound | molecular function regulator | metal ion homeostasis | voluntary musculoskeletal movement | response to nitrogen compound | apoptotic process | response to oxygen levels | regulation of signal transduction | channel inhibitor activity | multicellular organism development | calcium ion transmembrane transport | response to purine-containing compound | ion transmembrane transport | cellular response to stress | cation transmembrane transporter activity | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | second-messenger-mediated signaling | negative regulation of sequestering of calcium ion | post-embryonic development | cation homeostasis | cellular cation homeostasis | cell communication | cellular calcium ion homeostasis | homeostatic process | calcium-release channel activity | positive regulation of transport | apoptotic signaling pathway | release of sequestered calcium ion into cytosol | calcium-mediated signaling | cation transmembrane transport | calcium channel regulator activity | response to organic substance | epithelial fluid transport | metal ion transmembrane transporter activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | chemical homeostasis | calcium ion transport | regulation of sequestering of calcium ion | cell death | positive regulation of ion transport | ion homeostasis | cellular response to cAMP | inorganic cation transmembrane transport | response to cAMP | cation channel activity | regulation of cell communication | negative regulation of signal transduction | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | response to organic cyclic compound | intracellular ligand-gated ion channel activity | calcium channel inhibitor activity | cation transport | channel activity | regulation of ion transport | endoplasmic reticulum calcium ion homeostasis | developmental process | calcium channel activity | regulation of calcium ion transport | regulation of transport | response to organonitrogen compound | cellular metal ion homeostasis | ion channel activity | ion transport | cellular response to organic substance | regulation of cell death | negative regulation of cell death | divalent inorganic cation homeostasis | substrate-specific channel activity | positive regulation of calcium ion transport | signal transduction | regulation of signaling | multicellular organismal process
GO Cellular Component
secretory granule | integral component of membrane | organelle inner membrane | sarcoplasmic reticulum | dendrite | intracellular membrane-bounded organelle | synapse | catalytic complex | neuron projection | somatodendritic compartment | organelle membrane | nuclear membrane | cytoplasmic vesicle | cell body | cell | platelet dense granule | nuclear lumen | neuronal cell body | nuclear inner membrane | intrinsic component of membrane | synaptic membrane | nucleolus | cytoplasm | intracellular organelle | endoplasmic reticulum | membrane microdomain | dendritic tree | secretory granule membrane | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | cell projection | secretory vesicle | endomembrane system | endoplasmic reticulum membrane | postsynapse | plasma membrane | nuclear envelope | membrane raft | vesicle | perinuclear region of cytoplasm | postsynaptic density | asymmetric synapse | protein serine/threonine phosphatase complex | platelet dense tubular network | membrane-bounded organelle | platelet dense granule membrane | nucleus | organelle | postsynaptic specialization | vesicle membrane | sarcoplasm | calcineurin complex | cell periphery | membrane-enclosed lumen | intracellular vesicle | intracellular | membrane | cytoplasmic vesicle membrane
