QuickView for orexin A (gene)

Gene Symbol:

Hcrt Mus musculus

Full name:

hypocretin

Synonyms:

PPOX, orexin, orexin A, orexin B, prepro-orexin

Genomic Location:

Chr 11: 100623007-100624245

Description:

This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors Hcrtr1 and Hcrtr2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role ...

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This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors Hcrtr1 and Hcrtr2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_01 ,  GATA3_01 ,  CHX10_01 ,  SMAD3_Q6 ,  RNCTGNYNRNCTGNY_UNKNOWN ,  WTTGKCTG_UNKNOWN ,  TAATTA_CHX10_01 ,  CTTTGT_LEF1_Q2 ,  TATAAA_TATA_01

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