QuickView for p38 MAPK (gene)
- Gene Symbol:
- Mapk14
Mus musculus - Full name:
- mitogen-activated protein kinase 14
- Synonyms:
- CSBP2, Crk1, Csbp1, Mxi2, PRKM14, PRKM15, p38, p38-alpha, p38MAPK, p38a, p38alpha, mitogen-activated protein kinase 14, MAP kinase 14, MAP kinase p38 alpha, MAPK 14, mitogen-activated protein kinase p38 alpha, p38 MAP kinase alpha, p38 MAPK
- Genomic Location:
- Chr 17: 28828390-28885350
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Canis lupus familiaris , Gallus gallus , Pan troglodytes , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-125 , Predicted Gene Targets for miR-128 , Predicted Gene Targets for miR-142-5p , Predicted Gene Targets for miR-185 , Predicted Gene Targets for miR-19 , Predicted Gene Targets for miR-22 , Predicted Gene Targets for miR-224 , Predicted Gene Targets for miR-27 , Predicted Gene Targets for miR-124a , Predicted Gene Targets for miR-124u
GO Molecular Function
kinase binding | protein kinase binding | mitogen-activated protein kinase p38 binding | enzyme binding | mitogen-activated protein kinase binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | NFAT protein binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | MAP kinase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein phosphatase binding | transcription factor binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | phosphatase binding | heterocyclic compound binding | protein C-terminus binding | small molecule binding
GO Biological Process
positive regulation of immune response | positive regulation of cyclase activity | RNA metabolic process | regulation of leukocyte chemotaxis | positive regulation of erythrocyte differentiation | positive regulation of striated muscle cell differentiation | regulation of myoblast fusion | response to radiation | cell morphogenesis | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | regulation of intracellular protein transport | response to virus | response to cytokine | positive regulation of cellular component organization | response to lipopolysaccharide | developmental process involved in reproduction | regulation of cellular localization | muscle tissue development | intracellular signal transduction | regulation of localization | positive regulation of striated muscle tissue development | peptidyl-amino acid modification | regulation of immune system process | myeloid cell differentiation | negative regulation of cellular process | positive regulation of developmental process | glucose metabolic process | cellular response to tumor necrosis factor | regulation of heart growth | regulation of protein import | cell differentiation | response to drug | positive regulation of cellular component movement | positive regulation of protein secretion | blood vessel morphogenesis | regulation of cardiac muscle cell proliferation | positive regulation of cellular biosynthetic process | cellular process | positive regulation of macrophage migration | regulation of glucose import | regulation of cell motility | regulation of syncytium formation by plasma membrane fusion | negative regulation of signaling | developmental growth | positive regulation of immune effector process | positive regulation of reactive oxygen species metabolic process | reproductive system development | immune system development | regulation of striated muscle tissue development | regulation of chemotaxis | regulation of proteolysis | regulation of cell cycle | response to growth factor | positive regulation of catalytic activity | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | regulation of canonical Wnt signaling pathway | tissue development | regulation of fat cell differentiation | regulation of cell differentiation | positive regulation of muscle cell differentiation | muscle structure development | muscle cell differentiation | skeletal muscle organ development | regulation of myotube differentiation | regeneration | regulation of immune response | regulation of cellular process | cellular response to lipid | regulation of metabolic process | cellular response to molecule of bacterial origin | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | cellular lipid metabolic process | MAPK cascade | regulation of peptide secretion | stress-induced premature senescence | response to stimulus | vasculature development | cellular response to vascular endothelial growth factor stimulus | cartilage condensation | regulation of cellular protein localization | monocarboxylic acid metabolic process | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of peptidase activity | signal transduction by protein phosphorylation | response to stress | positive regulation of cellular protein localization | skeletal muscle tissue development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | response to peptide | positive regulation of glucose import | response to muscle stretch | protein serine/threonine kinase activity | response to muramyl dipeptide | programmed cell death | reproduction | positive regulation of cytokine secretion | cardiovascular system development | positive regulation of proteolysis | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | positive regulation of myoblast differentiation | regulation of protein transport | positive regulation of RNA biosynthetic process | hemopoiesis | protein modification process | cartilage development | regulation of peptide transport | cellular biosynthetic process | macromolecule modification | regulation of intracellular transport | blood vessel development | stress-activated protein kinase signaling cascade | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | leukocyte differentiation | response to nitrogen compound | apoptotic process | response to external biotic stimulus | system development | chondrocyte differentiation | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | regulation of peptidase activity | phosphorus metabolic process | cellular response to DNA damage stimulus | positive regulation of muscle organ development | regulation of catalytic activity | lipid metabolic process | regulation of granulocyte chemotaxis | regulation of ossification | wound healing | signal transduction in response to DNA damage | regulation of gene expression | positive regulation of chemotaxis | osteoclast differentiation | positive regulation of secretion | cellular response to stress | response to lipid | positive regulation of intracellular protein transport | myeloid leukocyte differentiation | positive regulation of cellular metabolic process | regulation of interleukin-12 secretion | cellular response to radiation | animal organ morphogenesis | regulation of protein localization to nucleus | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | positive regulation of syncytium formation by plasma membrane fusion | enzyme linked receptor protein signaling pathway | monosaccharide metabolic process | small molecule metabolic process | positive regulation of interleukin-12 production | regulation of cellular component movement | regulation of transcription by RNA polymerase II | positive regulation of hydrolase activity | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | positive regulation of cell migration | cellular response to cytokine stimulus | positive regulation of glucose transmembrane transport | regulation of cytokine production involved in inflammatory response | positive regulation of protein localization to nucleus | biosynthetic process | positive regulation of cardiac muscle cell proliferation | stress-activated MAPK cascade | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | MAP kinase activity | angiogenesis | phosphorylation | carbohydrate metabolic process | positive regulation of brown fat cell differentiation | regulation of cyclase activity | protein phosphorylation | positive regulation of macrophage chemotaxis | regulation of leukocyte migration | phosphate-containing compound metabolic process | response to bacterium | striated muscle tissue development | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | skeletal system morphogenesis | positive regulation of leukocyte chemotaxis | regulation of cytokine production involved in immune response | regulation of protein metabolic process | lipid modification | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of locomotion | myoblast differentiation involved in skeletal muscle regeneration | regulation of RNA metabolic process | lipopolysaccharide-mediated signaling pathway | positive regulation of transport | cellular response to virus | striated muscle cell differentiation | cell aging | carboxylic acid metabolic process | p38MAPK cascade | positive regulation of molecular function | regulation of nucleocytoplasmic transport | regulation of cytokine secretion | positive regulation of organ growth | protein metabolic process | regulation of establishment of protein localization | regulation of growth | response to organic substance | regulation of cardiac muscle tissue development | regulation of protein import into nucleus | regulation of hemopoiesis | response to wounding | response to mechanical stimulus | cellular response to lipoteichoic acid | anatomical structure development | cell surface receptor signaling pathway | metabolic process | regulation of RNA biosynthetic process | hexose metabolic process | oxidation-reduction process | regulation of myoblast differentiation | regulation of cytokine secretion involved in immune response | positive regulation of cytokine production involved in immune response | regulation of erythrocyte differentiation | positive regulation of myoblast fusion | regulation of secretion | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | connective tissue development | cell death | regulation of glucose transmembrane transport | animal organ development | gene expression | regulation of protein secretion | positive regulation of leukocyte migration | cellular response to ionizing radiation | regulation of Wnt signaling pathway | regulation of striated muscle cell differentiation | positive regulation of cytokine secretion involved in immune response | fatty acid metabolic process | positive regulation of muscle tissue development | transcription, DNA-templated | positive regulation of cytokine production | positive regulation of intracellular transport | regulation of brown fat cell differentiation | lipid oxidation | positive regulation of protein transport | anatomical structure formation involved in morphogenesis | negative regulation of cell cycle | skeletal muscle tissue regeneration | regulation of cell communication | cellular senescence | negative regulation of signal transduction | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of transcription, DNA-templated | myoblast differentiation | regulation of developmental growth | organic acid metabolic process | cellular protein metabolic process | regulation of cytokine production | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | positive regulation of fat cell differentiation | positive regulation of protein import into nucleus | regulation of organ growth | response to biotic stimulus | reproductive structure development | regulation of developmental process | kinase activity | developmental process | negative regulation of canonical Wnt signaling pathway | regulation of muscle cell differentiation | positive regulation of protein import | peptidyl-serine phosphorylation | cell aggregation | cellular protein modification process | vascular endothelial growth factor receptor signaling pathway | tube development | regulation of transport | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | positive regulation of nucleic acid-templated transcription | positive regulation of heart growth | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | regulation of macrophage chemotaxis | fatty acid oxidation | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | skeletal system development | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | placenta development | response to tumor necrosis factor | cellular response to organic substance | regulation of protein localization | positive regulation of cardiac muscle tissue development | positive regulation of cell motility | DNA damage checkpoint | cell cycle checkpoint | positive regulation of metallopeptidase activity | circulatory system development | regulation of inflammatory response | aging | positive regulation of nucleocytoplasmic transport | tissue regeneration | positive regulation of interleukin-12 secretion | regulation of cellular component organization | response to ionizing radiation | muscle organ development | response to other organism | positive regulation of myotube differentiation | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | cellular response to lipopolysaccharide | regulation of muscle organ development | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | spindle | intracellular organelle | nuclear body | nucleoplasm | nuclear speck | microtubule cytoskeleton | mitochondrion | spindle pole | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | cytoskeleton | intracellular
