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QuickView for pirenzepine (compound)
PubChem
| Name: | Pirenzepine |
|---|---|
| PubChem Compound ID: | 11954384 |
| Description: | An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients. |
| Molecular formula: | C19H25Cl2N5O3 |
| Molecular weight: | 442.339 g/mol |
| Synonyms: |
Pirenzepine hydrochloride hydrate; Pirenzepine hydrochloride hydrate (JP15); Gastrozepin; D05276; Gastrozepin (TN)
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DrugBank
Identification
| Name: | Pirenzepine |
|---|---|
| Name (isomeric): | DB00670 |
| Drug Type: | small molecule |
| Description: | An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients. |
| Brand: | Pirenzepinum [INN-Latin], Pirenzepina [INN-Spanish], Pirenzepin, Pirenzepine Gastrozepin, Gastrozepin, Ulcosan, Bisvanil, Leblon, Tabe, Gasteril |
| Category: | Muscarinic Antagonists, Anti-Ulcer Agents, Antispasmodics, Antimuscarinics |
| CAS number: | 28797-61-7 |
Pharmacology
| Indication: | For the treatment of peptic ulcer, gastric ulcer, and duodenal ulcer. |
|---|---|
| Pharmacology: |
Pirenzepine belongs to a group of medications called antispasmodics/anticholinergics. These medications are used to relieve cramps or spasms of the stomach, intestines, and bladder. Pirenzepine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer....
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| Mechanism of Action: | Pirenzepine is a muscarinic receptor antagonist and binds to the muscarinic acetylcholine receptor. The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. |
| Affected organisms: | Humans and other mammals |
Interactions
| Food interaction: |
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Targets
