QuickView for soluble form (gene)
- Gene Symbol:
- Ctla4
Rattus norvegicus - Full name:
- cytotoxic T-lymphocyte-associated protein 4
- Synonyms:
- CTLA-4, Cd152, sCTLA4, cytotoxic T-lymphocyte protein 4, CD152 antigen, soluble form, transmembrane form
- Genomic Location:
- Chr 9: 59495773-59501300
- Description:
-
immunoregulatory receptor expressed on the surface of T and B lymphocytes
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Gallus gallus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
TAL1BETAITF2_01 , ARP1_01 , SRY_02 , NKX25_02 , GFI1_01 , FAC1_01 , FOXO3_01 , VDR_Q6 , AGCATTA_MIR155 , AAGCAAT_MIR137
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
signaling receptor activity | protein binding
GO Biological Process
positive regulation of immune response | negative regulation of lymphocyte differentiation | negative regulation of leukocyte activation | negative regulation of immune system process | regulation of B cell activation | immune response-regulating signaling pathway | positive regulation of apoptotic process | regulation of programmed cell death | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | negative regulation of cellular process | negative regulation of leukocyte cell-cell adhesion | immune response-activating cell surface receptor signaling pathway | regulation of T cell differentiation | negative regulation of B cell proliferation | cellular process | negative regulation of T cell proliferation | regulation of cell differentiation | regulation of immune response | regulation of cellular process | regulation of apoptotic process | negative regulation of mononuclear cell proliferation | response to stimulus | regulation of regulatory T cell differentiation | positive regulation of immune system process | negative regulation of cell adhesion | response to stress | negative regulation of lymphocyte activation | regulation of cell proliferation | immune response-activating signal transduction | negative regulation of hemopoiesis | regulation of cell adhesion | B cell receptor signaling pathway | regulation of lymphocyte differentiation | cellular response to DNA damage stimulus | regulation of T cell activation | cellular response to stress | regulation of lymphocyte activation | negative regulation of T cell activation | negative regulation of immune response | negative regulation of cell-cell adhesion | cell communication | negative regulation of cell activation | negative regulation of T cell differentiation | negative regulation of B cell activation | activation of immune response | regulation of hemopoiesis | cell surface receptor signaling pathway | negative regulation of leukocyte proliferation | positive regulation of cell death | immune response | regulation of cell activation | positive regulation of programmed cell death | antigen receptor-mediated signaling pathway | signaling | regulation of T cell proliferation | regulation of developmental process | regulation of B cell proliferation | negative regulation of cell proliferation | regulation of cell-cell adhesion | negative regulation of lymphocyte proliferation | immune system process | regulation of cell death | negative regulation of cell differentiation | signal transduction | negative regulation of regulatory T cell differentiation
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | clathrin-coated vesicle | cytoplasmic vesicle | cell | intrinsic component of membrane | external side of plasma membrane | cytoplasm | clathrin-coated endocytic vesicle | intracellular organelle | Golgi apparatus | protein-containing complex | endomembrane system | plasma membrane | vesicle | perinuclear region of cytoplasm | integral component of plasma membrane | membrane-bounded organelle | organelle | cell periphery | protein complex involved in cell adhesion | intracellular vesicle | cell surface | endocytic vesicle | intracellular | membrane | intrinsic component of plasma membrane | coated vesicle
