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PubChem
| Name: | Tyrosine |
|---|---|
| PubChem Compound ID: | 112163 |
| Description: | A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. |
| Molecular formula: | C9H9NNa2O3 |
| Molecular weight: | 225.152 g/mol |
| Synonyms: |
EINECS 274-152-3; 69847-45-6; L-Tyrosine, disodium salt; Disodium L-tyrosinate
|
DrugBank
Identification
| Name: | Tyrosine |
|---|---|
| Name (isomeric): | DB00135 |
| Drug Type: | small molecule |
| Description: | A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. |
| Synonyms: |
2-Amino-3-(p-hydroxyphenyl)propionic acid; Free-Form L-Tyrosine; 3-(p-Hydroxyphenyl)alanine
|
| Brand: | Rxosine, Tyrosine, Tyrosine Power |
| Category: | Micronutrient, Dietary supplement, Non-Essential Amino Acids |
| CAS number: | 60-18-4 |
Pharmacology
| Indication: | Tyrosine is claimed to act as an effective antidepressant, however results are mixed. Tyrosine has also been claimed to reduce stress and combat narcolepsy and chronic fatigue, however these claims have been refuted by some studies. |
|---|---|
| Pharmacology: |
Tyrosine is a nonessential amino acid synthesized in the body from phenylalanine. Tyrosine is critical for the production of the body's proteins, enzymes and muscle tissue. Tyrosine is a precursor to the neurotransmitters norepinephrine and dopamine. It can act as a mood elevator and an anti-depressant. It may improve memory and increase mental ale...
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| Mechanism of Action: |
Tyrosine is produced in cells by hydroxylating the essential amino acid phenylalanine. This relationship is much like that between cysteine and methionine. Half of the phenylalanine required goes into the production of tyrosine; if the diet is rich in tyrosine itself, the requirements for phenylalanine are reduced by about 50%. The mechanism of L-t...
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| Absorption: | L-tyrosine is absorbed from the small intestine by a sodium-dependent active transport process. |
| Biotransformation: | In the liver, L-tyrosine is involved in a number of biochemical reactions, including protein synthesis and oxidative catabolic reactions. L-tyrosine that is not metabolized in the liver is distributed via the systemic circulation to the various tissues of the body. |
| Toxicity: | L-Tyrosine has very low toxicity. There have been very few reports of toxicity. LD50 (oral, rat) > 5110 mg/kg. |
| Affected organisms: | Humans and other mammals |
Targets
Transporters
