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QuickView for urea (compound)


PubChem
Name: Urea
PubChem Compound ID: 1176
Description: A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Molecular formula: CH4N2O
Molecular weight: 60.0553 g/mol
Synonyms:
Urepearl; Aquacare HP; Carmol 40; Alphadrate; DivK1c_000086; B-I-K; 173144-80-4; Aquacare; Carbamide; component of Artra Ashy Skin Cream.
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DrugBank
Identification
Name: Urea
Name (isomeric): DB03904
Drug Type: small molecule
Description: A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
CAS number: 57-13-6
Pharmacology
Indication: <ul> <li>10% hydrate skin</li> <li>15% accelerate fibrin degradation</li> <li>20-30% are antipruritic, break down keratin, decrease the thickness of the stratum corneum and are used in scaling conditions such as ichthysosis</li> <li>40% are proteolytic and may be used to dissolve and peel dystrophic nails</li> </ul> <br>[Patient Self Care, 2010]</br>
Pharmacology: As a humectant, urea draws water into the striatum corneum.
Interactions
Drug interaction:
TreprostinilAdditive hypotensive effect. Monitor antihypertensive therapy during concomitant use.

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