QuickView for AKR1B1;jsessionid=C4681D31174458374280C3808068A691;jsessionid=2D03969CE0D0C082DED7D7D5B0667384 (gene)
- Gene Symbol:
- Akr1b3
Mus musculus - Full name:
- aldo-keto reductase family 1, member B3 (aldose reductase)
- Synonyms:
- ALR2, AR, Ahr-1, Ahr1, Akr1b1, Aldor1, Aldr1, aldose reductase, aldehyde reductase 1, aldo-keto reductase family 1, member B1 (aldose reductase)
- Genomic Location:
- Chr 6: 34253934-34267471
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Bos taurus , Danio rerio , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
oxidoreductase activity, acting on CH-OH group of donors | glyceraldehyde oxidoreductase activity | alcohol dehydrogenase (NADP+) activity | aldo-keto reductase (NADP) activity | catalytic activity | alditol:NADP+ 1-oxidoreductase activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | oxidoreductase activity
GO Biological Process
positive regulation of smooth muscle cell proliferation | hyperosmotic response | oxidoreductase activity, acting on CH-OH group of donors | sorbitol biosynthetic process | intracellular signal transduction | catechol-containing compound metabolic process | regulation of programmed cell death | negative regulation of cellular process | response to water | response to drug | renal water homeostasis | naphthalene metabolic process | polyol metabolic process | response to antibiotic | tissue homeostasis | phenol-containing compound metabolic process | cellular process | glyceraldehyde oxidoreductase activity | negative regulation of apoptotic process | response to inorganic substance | anatomical structure homeostasis | response to hydrogen peroxide | cellular hyperosmotic salinity response | regulation of cellular process | regulation of apoptotic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | regulation of urine volume | urogenital system development | alcohol dehydrogenase (NADP+) activity | response to stimulus | collecting duct development | response to salt stress | response to stress | positive regulation of JAK-STAT cascade | alcohol metabolic process | regulation of cell proliferation | multicellular organismal homeostasis | aldo-keto reductase (NADP) activity | cellular response to toxic substance | cofactor metabolic process | cellular biosynthetic process | kidney development | stress-activated protein kinase signaling cascade | water homeostasis | organic hydroxy compound metabolic process | system development | nitrogen compound metabolic process | regulation of signal transduction | cellular response to antibiotic | multicellular organism development | antibiotic metabolic process | cellular response to oxidative stress | response to ketone | cellular response to stress | monosaccharide metabolic process | small molecule metabolic process | cellular carbohydrate metabolic process | positive regulation of STAT cascade | positive regulation of intracellular signal transduction | response to oxidative stress | daunorubicin metabolic process | carbohydrate biosynthetic process | cellular ketone metabolic process | biosynthetic process | response to osmotic stress | alditol:NADP+ 1-oxidoreductase activity | norepinephrine metabolic process | carbohydrate metabolic process | response to toxic substance | response to methylglyoxal | cellular response to drug | cell communication | positive regulation of signal transduction | homeostatic process | positive regulation of cell proliferation | renal system development | cellular hyperosmotic response | drug metabolic process | response to organic substance | inner medullary collecting duct development | regulation of JAK-STAT cascade | catecholamine metabolic process | cellular response to osmotic stress | regulation of intracellular signal transduction | anatomical structure development | metabolic process | regulation of body fluid levels | oxidation-reduction process | negative regulation of programmed cell death | cellular response to hydrogen peroxide | doxorubicin metabolic process | chemical homeostasis | sorbitol metabolic process | glycoside metabolic process | cellular response to reactive oxygen species | organic substance metabolic process | animal organ development | response to reactive oxygen species | cellular response to salt stress | renal system process | hyperosmotic salinity response | response to water deprivation | regulation of cell communication | signaling | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | developmental process | tube development | carbohydrate derivative metabolic process | quinone metabolic process | multicellular organismal water homeostasis | cellular response to methylglyoxal | cellular metabolic process | cellular response to organic substance | regulation of cell death | regulation of smooth muscle cell proliferation | oxidoreductase activity | negative regulation of cell death | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | actin-based cell projection | cell | nuclear lumen | mast cell granule | compact myelin | cytoplasm | intracellular organelle | cell-cell junction | glial cell projection | cell projection | nucleoplasm | plasma membrane bounded cell projection cytoplasm | vacuole | perinuclear region of cytoplasm | cytoplasmic region | lytic vacuole | extracellular region | microvillus | membrane-bounded organelle | nucleus | organelle | lysosome | extracellular space | membrane-enclosed lumen | Schwann cell microvillus | paranodal junction | Schmidt-Lanterman incisure | cytosol | intracellular | cell junction | myelin sheath
