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QuickView for BMPR1B;jsessionid=DF3FB09F3D48514796170E68146687DE;jsessionid=370809DB7E11043C1537C770FA7B7D07;jsessionid=959406671FABA4E415C20AF5459E6B1D (gene)


Gene Symbol:
Bmpr1b Mus musculus Mus musculus
Full name:
bone morphogenetic protein receptor, type 1B
Synonyms:
AI385617, ALK-6, AV355320, Acvrlk6, Alk6, BMPR-1B, BMPR-IB, CFK-43a, SKR6, bone morphogenetic protein receptor type-1B, BMP type-1B receptor, activin receptor-like kinase 6, serine/threonine-protein kinase receptor R6
Genomic Location:
Chr 3: 141500100-141645215
Description:
This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type I receptor, and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important in skele...
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Bos taurus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

transforming growth factor beta-activated receptor activity | cation binding | transmembrane signaling receptor activity | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | transforming growth factor beta receptor activity, type I | growth factor binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | signaling receptor activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transmembrane receptor protein serine/threonine kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | SMAD binding | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

limb development | cell morphogenesis | positive regulation of macromolecule biosynthetic process | neuron projection morphogenesis | developmental process involved in reproduction | ovarian follicle development | positive regulation of apoptotic process | gonad development | regulation of programmed cell death | female gonad development | eye development | ovarian cumulus expansion | positive regulation of developmental process | cell differentiation | defense response | nervous system development | transforming growth factor beta-activated receptor activity | positive regulation of biomineral tissue development | cell part morphogenesis | estrogen biosynthetic process | neurogenesis | estrogen metabolic process | generation of neurons | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | cell projection morphogenesis | limb morphogenesis | developmental growth | neuron development | reproductive system development | multicellular organismal reproductive process | axon guidance | response to growth factor | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | positive regulation of nitrogen compound metabolic process | regulation of bone mineralization | tissue development | regulation of cell differentiation | gamete generation | regulation of cellular process | regulation of osteoblast differentiation | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | steroid biosynthetic process | cellular component organization | response to transforming growth factor beta | development of primary sexual characteristics | response to stimulus | female gamete generation | cell morphogenesis involved in neuron differentiation | cartilage condensation | response to stress | neuron projection guidance | germ cell development | ovulation cycle | protein serine/threonine kinase activity | development of primary female sexual characteristics | transforming growth factor beta receptor activity, type I | reproduction | rhythmic process | retinal ganglion cell axon guidance | positive regulation of RNA biosynthetic process | protein modification process | cartilage development | cellular biosynthetic process | dorsal/ventral pattern formation | macromolecule modification | regulation of nucleic acid-templated transcription | locomotion | response to BMP | system development | chondrocyte differentiation | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | phosphorus metabolic process | hormone biosynthetic process | antral ovarian follicle growth | lipid metabolic process | regulation of hormone levels | regulation of ossification | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | axon development | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | regulation of transcription by RNA polymerase II | oogenesis | axonogenesis | positive regulation of cell differentiation | biosynthetic process | positive regulation of ossification | phosphorylation | lipid biosynthetic process | regulation of apoptotic signaling pathway | protein phosphorylation | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | sensory organ development | ovulation cycle process | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | skeletal system morphogenesis | inflammatory response | positive regulation of signal transduction | regulation of RNA metabolic process | positive regulation of osteoblast differentiation | cellular response to transforming growth factor beta stimulus | neuron differentiation | multicellular organism reproduction | protein metabolic process | transmembrane receptor protein serine/threonine kinase activity | regionalization | response to organic substance | retina development in camera-type eye | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | regulation of RNA biosynthetic process | positive regulation of cell death | protein kinase activity | neuron projection development | organic substance metabolic process | connective tissue development | mammalian oogenesis stage | animal organ development | positive regulation of programmed cell death | camera-type eye development | transforming growth factor beta receptor signaling pathway | steroid metabolic process | BMP signaling pathway | regulation of cell communication | regulation of extrinsic apoptotic signaling pathway via death domain receptors | signaling | regulation of transcription, DNA-templated | cell development | cellular protein metabolic process | hormone metabolic process | anatomical structure morphogenesis | reproductive structure development | regulation of developmental process | kinase activity | developmental process | cell aggregation | cellular protein modification process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | cellular response to BMP stimulus | skeletal system development | cellular metabolic process | female sex differentiation | cellular response to organic substance | regulation of cell death | sex differentiation | chemotaxis | sexual reproduction | positive regulation of bone mineralization | positive regulation of apoptotic signaling pathway | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | receptor complex | protein-containing complex | plasma membrane | integral component of plasma membrane | cell periphery | membrane | intrinsic component of plasma membrane