QuickView for CASP9;jsessionid=B0C7DBB2DDBED44A041162B5327E8C75;jsessionid=F11CA2D50185B0267E875D2139E1E58B;jsessionid=999F32D08B38BA7ACFDD4A499F28B702 (gene)

Gene Symbol:

Casp9 Mus musculus

Full name:

caspase 9

Synonyms:

AI115399, APAF-3, AW493809, CASP-9, Caspase-9, ICE-LAP6, Mch6, caspase-9, ICE-like apoptotic protease 6, apoptotic protease Mch-6, apoptotic protease-activating factor 3

Genomic Location:

Chr 4: 141349527-141371890

Description:

This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This ...

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This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This protein may have a role in normal brain development. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

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