QuickView for CHRNA7;jsessionid=058F66292118E3B0A7C7A951F3C8B5BC;jsessionid=CB3BB734035A5D962F320C16EAF7AC97 (gene)
- Gene Symbol:
- Chrna7
Mus musculus - Full name:
- cholinergic receptor, nicotinic, alpha polypeptide 7
- Synonyms:
- Acra7, alpha7, nAchR, neuronal acetylcholine receptor subunit alpha-7, acetylcholine receptor alpha 7 neural, alpha7 nicotinic receptor, alpha7-nAChR
- Genomic Location:
- Chr 7: 70243578-70357404
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Bos taurus , Gallus gallus , Danio rerio , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
transmitter-gated ion channel activity | kinase binding | acetylcholine-gated cation-selective channel activity | neurotransmitter receptor activity | peptide binding | channel regulator activity | amyloid-beta binding | cation binding | adenylate cyclase binding | passive transmembrane transporter activity | protein kinase binding | neurotransmitter binding | transmembrane signaling receptor activity | enzyme binding | toxic substance binding | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | chloride channel regulator activity | molecular function regulator | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | ATPase binding | cation transmembrane transporter activity | acetylcholine receptor activity | amide binding | signaling receptor activity | transporter activity | identical protein binding | ion transmembrane transporter activity | scaffold protein binding | extracellular ligand-gated ion channel activity | ion binding | acetylcholine binding | hormone binding | protein binding | protein homodimerization activity | protein dimerization activity | excitatory extracellular ligand-gated ion channel activity | cation channel activity | inorganic cation transmembrane transporter activity | channel activity | drug binding | ion channel activity | substrate-specific channel activity
GO Biological Process
transmitter-gated ion channel activity | positive regulation of heart contraction | response to extracellular stimulus | negative regulation of amyloid-beta formation | regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | regulation of supramolecular fiber organization | regulation of interleukin-1 beta production | positive regulation of acetylcholine metabolic process | cell morphogenesis | positive regulation of hormone biosynthetic process | positive regulation of amyloid precursor protein catabolic process | response to nutrient levels | negative regulation of MAPK cascade | positive regulation of blood circulation | cell motility | neuron projection morphogenesis | acetylcholine-gated cation-selective channel activity | regulation of localization | neuron projection arborization | establishment of localization | response to hormone | negative regulation of cellular process | positive regulation of developmental process | regulation of MAP kinase activity | regulation of acetylcholine metabolic process | cell differentiation | excitatory postsynaptic potential | nervous system development | response to drug | negative regulation of protein phosphorylation | cellular chemical homeostasis | cell part morphogenesis | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | response to antibiotic | flagellated sperm motility | regulation of neuron death | positive regulation of neurological system process | positive regulation of cellular biosynthetic process | cellular process | regulation of catecholamine secretion | negative regulation of inflammatory response | channel regulator activity | localization | cellular homeostasis | cell projection morphogenesis | positive regulation of synaptic transmission | passive transmembrane transporter activity | acetylcholine receptor signaling pathway | negative regulation of signaling | metal ion transport | chemical synaptic transmission | positive regulation of peptidyl-serine phosphorylation | neuron development | dendritic spine organization | multicellular organismal reproductive process | learning | positive regulation of protein kinase activity | response to hypoxia | positive regulation of catalytic activity | dendrite arborization | sensory processing | positive regulation of nitrogen compound metabolic process | positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure | negative regulation of cellular metabolic process | regulation of neurological system process | regulation of angiogenesis | regulation of cellular process | leukocyte activation | negative regulation of interleukin-1 production | regulation of metabolic process | transmembrane transporter activity | neurological system process involved in regulation of systemic arterial blood pressure | negative regulation of tumor necrosis factor production | positive regulation of cellular protein metabolic process | ligand-gated ion channel activity | cellular component organization | behavioral response to nicotine | calcium ion homeostasis | T cell activation | associative learning | regulation of vasculature development | response to stimulus | positive regulation of blood pressure | ion gated channel activity | cell morphogenesis involved in neuron differentiation | regulation of long-term synaptic potentiation | positive regulation of protein metabolic process | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | response to cold | regulation of norepinephrine secretion | positive regulation of acetylcholine biosynthetic process | response to stress | negative regulation of tumor necrosis factor superfamily cytokine production | regulation of cell proliferation | ovulation cycle | regulation of blood circulation | response to peptide | positive regulation of long-term synaptic potentiation | sperm motility | regulation of heart rate | reproduction | divalent metal ion transport | response to alcohol | response to temperature stimulus | rhythmic process | blood circulation | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | neuronal action potential | chloride channel regulator activity | regulation of systemic arterial blood pressure by baroreceptor feedback | regulation of synapse structure or activity | modulation of chemical synaptic transmission | negative regulation of amyloid precursor protein catabolic process | cell-cell signaling | negative regulation of ERK1 and ERK2 cascade | activation of protein kinase activity | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | metal ion homeostasis | response to ethanol | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | regulation of membrane potential | regulation of neurotransmitter levels | locomotion | response to nitrogen compound | cellular response to hormone stimulus | response to nicotine | system development | response to oxygen levels | reproductive process | regulation of signal transduction | generation of ovulation cycle rhythm | modulation of excitatory postsynaptic potential | negative regulation of phosphate metabolic process | regulation of synaptic transmission, cholinergic | negative regulation of interleukin-6 production | multicellular organism development | regulation of MAPK cascade | learning or memory | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of hormone levels | ion transmembrane transport | cellular response to ammonium ion | regulation of postsynaptic membrane potential | nervous system process | regulation of blood pressure | synaptic signaling | cation transmembrane transporter activity | regulation of systemic arterial blood pressure | negative regulation of cytokine production | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | behavioral response to ethanol | response to ammonium ion | response to acetylcholine | regulation of synapse organization | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | vesicle-mediated transport | synapse organization | ion transmembrane transporter activity | regulation of synaptic transmission, dopaminergic | cognition | B cell activation | regulation of hormone metabolic process | regulation of cellular protein metabolic process | extracellular ligand-gated ion channel activity | response to toxic substance | regulation of heart contraction | regulation of tumor necrosis factor production | regulation of amyloid precursor protein catabolic process | cell morphogenesis involved in differentiation | cation homeostasis | ovulation cycle process | cellular response to drug | regulation of interleukin-1 production | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of synapse structural plasticity | regulation of protein metabolic process | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | positive regulation of systemic arterial blood pressure | lymphocyte activation | positive regulation of molecular function | neuron differentiation | multicellular organism reproduction | activation of MAPK activity | cation transmembrane transport | positive regulation of heart rate | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | import into cell | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | regulation of amyloid fibril formation | chemical homeostasis | calcium ion transport | endocytosis | regulation of secretion | behavior | neuron projection development | excitatory extracellular ligand-gated ion channel activity | negative regulation of cellular protein metabolic process | positive regulation of ERK1 and ERK2 cascade | positive regulation of kinase activity | ion homeostasis | regulation of phosphate metabolic process | positive regulation of CoA-transferase activity | cell activation | positive regulation of MAPK cascade | positive regulation of excitatory postsynaptic potential | cation channel activity | regulation of peptidyl-serine phosphorylation | dendrite morphogenesis | memory | adult behavior | negative regulation of protein metabolic process | sensory perception | regulation of cell communication | negative regulation of signal transduction | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | response to amyloid-beta | regulation of amyloid-beta formation | cell development | positive regulation of phosphorylation | regulation of cytokine production | anatomical structure morphogenesis | cation transport | channel activity | positive regulation of MAP kinase activity | dendrite development | regulation of developmental process | developmental process | negative regulation of interleukin-1 beta production | regulation of transport | synaptic transmission, cholinergic | response to organonitrogen compound | cellular metal ion homeostasis | transmission of nerve impulse | ion channel activity | positive regulation of metabolic process | regulation of synaptic plasticity | ion transport | immune system process | positive regulation of amyloid-beta formation | cellular response to organic substance | regulation of cell death | response to food | regulation of interleukin-6 production | regulation of inflammatory response | divalent inorganic cation homeostasis | substrate-specific channel activity | positive regulation of angiogenesis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | regulation of hormone biosynthetic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
presynaptic membrane | dendritic spine | integral component of membrane | dendrite | synapse | apical plasma membrane | neuron projection | axolemma | somatodendritic compartment | cell projection membrane | cell body | cell | neuronal cell body | plasma membrane protein complex | distal axon | intrinsic component of membrane | synaptic membrane | external side of plasma membrane | cytoplasm | receptor complex | membrane microdomain | dendritic tree | leading edge membrane | main axon | apical part of cell | presynapse | protein-containing complex | cell projection | postsynaptic membrane | neuron spine | postsynapse | plasma membrane | cell leading edge | membrane raft | postsynaptic density | asymmetric synapse | site of polarized growth | integral component of plasma membrane | dendritic shaft | organelle | postsynaptic specialization | cell periphery | axon | transmembrane transporter complex | growth cone | plasma membrane raft | ion channel complex | cell surface | intracellular | cell junction | acetylcholine-gated channel complex | membrane | neuron projection membrane | intrinsic component of plasma membrane
