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QuickView for CLCA2;jsessionid=53CA6A2F744C5C7317278616728B444B;jsessionid=39CCC175DD7DBF0BDADF4F444B0549BE;jsessionid=1284385793C2D06BE0B4DAF47318EF87 (gene)


Gene Symbol:
Clca2 Mus musculus Mus musculus
Full name:
chloride channel accessory 2
Synonyms:
4732440A06, AI586120, Clca5, calcium-activated chloride channel regulator 2, calcium-activated chloride channel family member 5
Genomic Location:
Chr 3: 144733229-144762005
Description:
This gene encodes a member of the calcium-activated chloride channel regulator (CLCR) family of proteins. Members of this family regulate the transport of chloride across the plasma membrane. Expression of this gene is upregulated by the tumor suppressor protein p53 in response to DNA damage. Mice lacking a functional copy of this gene exhibit incr...
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Bos taurus Canis lupus familiaris Pan troglodytes Gallus gallus
External Links:
Entrez Gene





GO Molecular Function

metallopeptidase activity | anion transmembrane transporter activity | cation binding | passive transmembrane transporter activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | hydrolase activity | chloride channel activity | intracellular calcium activated chloride channel activity | inorganic anion transmembrane transporter activity | catalytic activity | chloride transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | ion binding | anion channel activity | channel activity | metal ion binding | ion channel activity | peptidase activity | substrate-specific channel activity

GO Biological Process

metallopeptidase activity | proteolysis | establishment of localization | anion transmembrane transporter activity | localization | passive transmembrane transporter activity | anion transport | transmembrane transporter activity | ligand-gated ion channel activity | chloride transmembrane transport | ion gated channel activity | chloride channel activity | chloride transport | inorganic anion transport | intracellular calcium activated chloride channel activity | inorganic anion transmembrane transporter activity | nitrogen compound metabolic process | chloride transmembrane transporter activity | ion transmembrane transport | ion transmembrane transporter activity | protein metabolic process | anion transmembrane transport | metabolic process | anion channel activity | cell adhesion | organic substance metabolic process | transmembrane transport | channel activity | ion channel activity | ion transport | peptidase activity | substrate-specific channel activity | macromolecule metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endomembrane system | plasma membrane | nuclear envelope | integral component of plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | cytosol | intracellular | cell junction | membrane | intrinsic component of plasma membrane