QuickView for CYBB;jsessionid=CFA0FC713E82BE062E17FE9E202B6173;jsessionid=6DD5F38F51BD009EC2008B205A5428F4;jsessionid=CCE7CFB139498398AB3B8348175ECC82 (gene)
- Gene Symbol:
- Cybb
Rattus norvegicus - Full name:
- cytochrome b-245 beta chain
- Synonyms:
- Gp91-phox, Nox2, cytochrome b-245 beta chain, NADPH oxidase 2, cytochrome b-245, beta polypeptide, endothelial type gp91-phox
- Genomic Location:
- Chr X: 25514572-25547181
- Description:
-
subunit of coronary microvascular endothelial cell NAD(P)H oxidase
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
oxidoreductase activity, acting on NAD(P)H | cofactor binding | superoxide-generating NADPH oxidase activity | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | catalytic activity | anion binding | electron transfer activity | protein heterodimerization activity | ion binding | organic cyclic compound binding | tetrapyrrole binding | protein binding | protein dimerization activity | heme binding | NAD(P)H oxidase activity | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
response to extracellular stimulus | cellular response to decreased oxygen levels | positive regulation of macromolecule biosynthetic process | oxidoreductase activity, acting on NAD(P)H | response to nutrient levels | superoxide metabolic process | response to hormone | positive regulation of developmental process | response to metal ion | defense response | cellular response to extracellular stimulus | response to drug | reactive oxygen species metabolic process | generation of precursor metabolites and energy | response to antibiotic | hydrogen peroxide biosynthetic process | positive regulation of cellular biosynthetic process | cellular process | regulation of cytokine biosynthetic process | superoxide-generating NADPH oxidase activity | response to hypoxia | positive regulation of nitrogen compound metabolic process | response to inorganic substance | response to peptide hormone | cellular response to L-glutamine | regulation of angiogenesis | regulation of cellular process | regulation of metabolic process | cellular response to organonitrogen compound | superoxide anion generation | cellular response to metal ion | positive regulation of tumor necrosis factor production | regulation of vasculature development | response to stimulus | positive regulation of protein metabolic process | cellular response to hypoxia | response to stress | electron transport chain | response to peptide | positive regulation of cytokine biosynthetic process | cellular response to inorganic substance | response to alcohol | cellular response to cadmium ion | cellular response to toxic substance | cellular response to ethanol | cofactor metabolic process | reactive oxygen species biosynthetic process | cellular biosynthetic process | response to ethanol | response to nitrogen compound | cellular response to nutrient levels | response to oxygen levels | cellular response to antibiotic | antibiotic metabolic process | response to amino acid | electron transfer activity | response to ketone | cellular response to stress | response to lipid | positive regulation of cellular metabolic process | cofactor biosynthetic process | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | response to corticosteroid | response to nutrient | biosynthetic process | response to cadmium ion | response to toxic substance | cellular response to amino acid stimulus | regulation of tumor necrosis factor production | cellular response to drug | cell communication | regulation of cellular metabolic process | inflammatory response | regulation of protein metabolic process | response to aldosterone | hypoxia-inducible factor-1alpha signaling pathway | drug metabolic process | response to angiotensin | cellular response to nutrient | response to organic substance | metabolic process | response to mineralocorticoid | oxidation-reduction process | immune response | regulation of tumor necrosis factor biosynthetic process | positive regulation of cytokine production | respiratory burst | signaling | response to organic cyclic compound | regulation of cytokine production | regulation of developmental process | positive regulation of tumor necrosis factor biosynthetic process | NAD(P)H oxidase activity | innate immune response | response to organonitrogen compound | hydrogen peroxide metabolic process | positive regulation of metabolic process | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor | immune system process | cellular metabolic process | cellular response to organic substance | oxidoreductase activity | response to steroid hormone | positive regulation of angiogenesis | signal transduction
GO Cellular Component
integral component of membrane | dendrite | intracellular membrane-bounded organelle | catalytic complex | neuron projection | somatodendritic compartment | NADPH oxidase complex | cytoplasmic vesicle | cell body | cell | oxidoreductase complex | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | dendritic tree | Golgi apparatus | protein-containing complex | cell projection | endomembrane system | plasma membrane | nuclear envelope | vesicle | perinuclear region of cytoplasm | integral component of plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | rough endoplasmic reticulum | intracellular vesicle | endocytic vesicle | intracellular | membrane | intrinsic component of plasma membrane | phagocytic vesicle
