QuickView for CYP11B2;jsessionid=424C622C3DFB936363F0465D0BEC631B;jsessionid=ED4AAB0A4FEB9DA7A2304A52A08699D4;jsessionid=BE8E8B7DB7EE2BEE29105772B35B7038;jsessionid=959A7F7E14209C132EC3BAC0492CBA30 (gene)
- Gene Symbol:
- Cyp11b2
Rattus norvegicus - Full name:
- cytochrome P450, family 11, subfamily b, polypeptide 2
- Synonyms:
- Cp45as, Cyp11b3, RNCP45AS, cytochrome P450 11B2, mitochondrial, CYPXIB2, CYPXIB3, Cytochrome P450, subfamily XIB, polypeptide 2 (aldosterone synthase), P450-Aldo-1, P450-Aldo-2, aldosterone synthase, cytochrome P450 11B3, mitochondrial, cytochrome P450, subfamily 11B, polypeptide 2, cytochrome P450-Aldo-1, cytochrome P450-Aldo-2, steroid 11-beta-hydroxylase
- Genomic Location:
- Chr 7: 113043365-113049773
- Description:
-
steroid 11-beta-monooxygenase that catalyzes steps in the biosynthesis of aldosterone, corticosterone, and 18-hydroxycorticosterone
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
| Protein Names |
|---|
| No proteins found. |
GO Molecular Function
cofactor binding | cation binding | steroid hydroxylase activity | iron ion binding | corticosterone 18-monooxygenase activity | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | tetrapyrrole binding | transition metal ion binding | heme binding | steroid 11-beta-monooxygenase activity | metal ion binding | heterocyclic compound binding | oxidoreductase activity
GO Biological Process
response to extracellular stimulus | response to nutrient levels | response to hormone | response to potassium ion | response to metal ion | cellular response to extracellular stimulus | response to drug | cellular response to potassium ion starvation | sterol metabolic process | cellular process | cellular response to potassium ion | cellular response to starvation | response to inorganic substance | response to peptide hormone | steroid hydroxylase activity | organic cyclic compound metabolic process | cellular response to organonitrogen compound | steroid biosynthetic process | cellular response to metal ion | response to stimulus | positive regulation of blood pressure | cellular response to mechanical stimulus | response to salt stress | response to stress | corticosterone 18-monooxygenase activity | alcohol metabolic process | response to peptide | response to starvation | cellular response to inorganic substance | blood circulation | cellular biosynthetic process | organic hydroxy compound metabolic process | response to nitrogen compound | cellular response to hormone stimulus | cellular response to nutrient levels | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | cellular response to peptide hormone stimulus | hormone biosynthetic process | lipid metabolic process | regulation of hormone levels | cellular response to stress | cellular response to peptide | regulation of blood pressure | small molecule metabolic process | response to nutrient | cellular ketone metabolic process | biosynthetic process | response to osmotic stress | lipid biosynthetic process | cell communication | mineralocorticoid biosynthetic process | drug metabolic process | cellular aldehyde metabolic process | cellular response to nutrient | response to organic substance | response to mechanical stimulus | cortisol metabolic process | response to insulin | metabolic process | cholesterol metabolic process | oxidation-reduction process | organic substance metabolic process | C21-steroid hormone metabolic process | steroid metabolic process | glucocorticoid metabolic process | hormone metabolic process | C21-steroid hormone biosynthetic process | glucocorticoid biosynthetic process | steroid 11-beta-monooxygenase activity | response to organonitrogen compound | aldosterone biosynthetic process | cellular metabolic process | cellular response to organic substance | oxidoreductase activity | cortisol biosynthetic process | multicellular organismal process
GO Cellular Component
organelle inner membrane | dendrite | intracellular membrane-bounded organelle | mitochondrial inner membrane | neuron projection | somatodendritic compartment | organelle membrane | cell | cytoplasm | intracellular organelle | dendritic tree | cell projection | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane
