QuickView for Cdc42Hs;jsessionid=48E172803A28E9CEB999B4ADA55C2D70;jsessionid=D649CBE55BA076D221AEE3258F54190C (gene)
- Gene Symbol:
- Cdc42
Rattus norvegicus - Full name:
- cell division cycle 42
- Synonyms:
- cell division control protein 42 homolog, cell division cycle 42 (GTP binding protein), cell division cycle 42 homolog
- Genomic Location:
- Chr 5: 156106122-156124006
- Description:
-
small GTPase; involved in formation of cellular asymmetry
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Gallus gallus , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-1 , Predicted Gene Targets for miR-128 , Predicted Gene Targets for miR-133 , Predicted Gene Targets for miR-18 , Predicted Gene Targets for miR-185 , Predicted Gene Targets for miR-186 , Predicted Gene Targets for miR-141 , Predicted Gene Targets for miR-224 , Predicted Gene Targets for miR-25 , Predicted Gene Targets for miR-27
GO Molecular Function
kinase binding | guanyl ribonucleotide binding | ribonucleoside binding | protein kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | signaling receptor binding | hydrolase activity | GTP-dependent protein binding | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | apolipoprotein A-I receptor binding | protein domain specific binding | ubiquitin-like protein transferase activity | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | identical protein binding | ubiquitin protein ligase activity | Rho GDP-dissociation inhibitor binding | thioesterase binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | GBD domain binding | apolipoprotein receptor binding | purine ribonucleoside triphosphate binding | GDP-dissociation inhibitor binding | mitogen-activated protein kinase kinase kinase binding | protein binding | ubiquitin-protein transferase activity | GTP binding | hydrolase activity, acting on acid anhydrides | transferase activity | ubiquitin-like protein ligase activity | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding
GO Biological Process
regulation of supramolecular fiber organization | molting cycle | cell morphogenesis | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | regulation of intracellular protein transport | heart process | dendritic spine development | actin filament-based process | microtubule-based transport | epidermis morphogenesis | response to cytokine | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | positive regulation of filopodium assembly | ectodermal placode formation | neuron projection morphogenesis | regulation of cellular localization | muscle tissue development | intracellular signal transduction | positive regulation of apoptotic process | regulation of cell development | phagocytosis, engulfment | regulation of localization | actin filament bundle organization | morphogenesis of an epithelium | regulation of programmed cell death | actin cytoskeleton organization | establishment of localization | regulation of cell shape | negative regulation of cellular process | integrin-mediated signaling pathway | positive regulation of developmental process | cell differentiation | positive regulation of epithelial cell proliferation | defense response | nervous system development | multicellular organism growth | hair follicle placode formation | cell part morphogenesis | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | positive regulation of hair follicle cell proliferation | regulation of DNA replication | regulation of organelle organization | establishment or maintenance of apical/basal cell polarity | generation of neurons | membrane organization | salivary gland morphogenesis | intracellular transport | actin filament branching | microtubule-based process | blood vessel morphogenesis | regulation of neuron death | positive regulation of phosphatidylinositol 3-kinase activity | regulation of attachment of spindle microtubules to kinetochore | regulation of chromosome segregation | positive regulation of cellular biosynthetic process | cellular process | regulation of epithelial cell proliferation involved in lung morphogenesis | establishment of organelle localization | localization | cell projection morphogenesis | developmental growth | positive regulation of peptidyl-serine phosphorylation | neuron development | canonical Wnt signaling pathway | dendritic spine organization | regulation of mitotic nuclear division | macromolecule localization | endomembrane system organization | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | positive regulation of cell division | establishment of localization in cell | tissue development | regulation of binding | regulation of cell differentiation | interspecies interaction between organisms | cell junction assembly | positive regulation of cytokinesis | cytoskeleton-dependent intracellular transport | positive regulation of lamellipodium assembly | morphogenesis of a polarized epithelium | regulation of cellular process | positive regulation of lamellipodium organization | positive regulation of cell growth | regulation of apoptotic process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | regulation of protein complex assembly | organelle localization | Golgi localization | polarized epithelial cell differentiation | heart contraction | small GTPase mediated signal transduction | positive regulation of cellular protein metabolic process | epithelium development | establishment of cell polarity | cellular component organization | viral life cycle | regulation of cell division | cellular response to interferon-gamma | sprouting angiogenesis | modification of synaptic structure | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | vasculature development | cell morphogenesis involved in neuron differentiation | regulation of cellular protein localization | positive regulation of protein metabolic process | gland morphogenesis | response to stress | organelle transport along microtubule | positive regulation of cellular protein localization | regulation of cell proliferation | positive regulation of actin filament bundle assembly | tube morphogenesis | cardiac muscle tissue development | epithelial cell development | response to glucose | supramolecular fiber organization | microtubule-based movement | cellular localization | cardiovascular system development | regulation of protein transport | blood circulation | negative regulation of metabolic process | dendritic cell migration | cellular component assembly | protein modification process | regulation of actin cytoskeleton reorganization | regulation of synapse structure or activity | regulation of peptide transport | regulation of cell adhesion | regulation of phosphatidylinositol 3-kinase activity | macromolecule modification | cell-cell signaling | regulation of intracellular transport | cell surface receptor signaling pathway involved in cell-cell signaling | Cdc42 protein signal transduction | blood vessel development | positive regulation of stress fiber assembly | leukocyte migration | neuron fate commitment | regulation of cellular response to stress | locomotion | regulation of cell projection assembly | system development | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | Wnt signaling pathway | regulation of protein stability | adherens junction organization | regulation of actin cytoskeleton organization | multicellular organism development | cell migration | positive regulation of DNA replication | regulation of MAPK cascade | regulation of actin filament organization | actin filament organization | regulation of catalytic activity | regulation of actomyosin structure organization | regulation of phosphorylation | hair follicle morphogenesis | positive regulation of cell cycle | regulation of gene expression | positive regulation of intracellular protein transport | cell projection assembly | viral genome replication | positive regulation of cellular metabolic process | positive regulation of actin cytoskeleton reorganization | positive regulation of protein phosphorylation | ectodermal placode development | epithelial-mesenchymal cell signaling | animal organ morphogenesis | cardiac conduction system development | regulation of synapse organization | keratinocyte development | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | regulation of cell-substrate adhesion | positive regulation of synapse structural plasticity | positive regulation of JNK cascade | positive regulation of cell projection organization | establishment or maintenance of monopolar cell polarity | positive regulation of intracellular signal transduction | vesicle-mediated transport | actin filament bundle assembly | ubiquitin protein ligase activity | synapse organization | positive regulation of cell differentiation | epidermal cell differentiation | cellular response to cytokine stimulus | cell division | regulation of cellular protein metabolic process | angiogenesis | positive regulation of neuron death | epidermis development | keratinization | skin development | cell morphogenesis involved in differentiation | positive regulation of pseudopodium assembly | keratinocyte differentiation | establishment or maintenance of cell polarity | regulation of lipid kinase activity | nuclear migration | striated muscle tissue development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of cytokinesis | regulation of synapse structural plasticity | regulation of neuron apoptotic process | positive regulation of cytoskeleton organization | regulation of protein metabolic process | positive regulation of signal transduction | heart development | positive regulation of cell proliferation | response to monosaccharide | positive regulation of establishment of protein localization | regulation of protein phosphorylation | positive regulation of transport | regulation of phospholipid metabolic process | viral process | regulation of filopodium assembly | regulation of mitotic cell cycle | positive regulation of molecular function | nucleus localization | neuron differentiation | regulation of cell morphogenesis involved in differentiation | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | regulation of growth | hair cycle | response to organic substance | gland development | protein ubiquitination | tissue morphogenesis | Rho protein signal transduction | Golgi organization | regulation of kinase activity | regulation of animal organ morphogenesis | import into cell | regulation of intracellular signal transduction | regulation of exocytosis | positive regulation of neuron apoptotic process | anatomical structure development | regulation of protein heterodimerization activity | cell surface receptor signaling pathway | submandibular salivary gland formation | cell projection organization | metabolic process | positive regulation of cell development | cell fate commitment | positive regulation of supramolecular fiber organization | ubiquitin-protein transferase activity | regulation of protein catabolic process | establishment or maintenance of epithelial cell apical/basal polarity | transport along microtubule | cellular protein localization | membrane invagination | regulation of vesicle-mediated transport | hair cycle process | endocytosis | regulation of secretion | positive regulation of cell death | cell adhesion | immune response | establishment of monopolar cell polarity | dendritic spine morphogenesis | neuron projection development | negative regulation of protein complex assembly | filopodium assembly | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of gene expression | animal organ development | positive regulation of cell-substrate adhesion | establishment of epithelial cell polarity | epithelial cell-cell adhesion | positive regulation of programmed cell death | positive regulation of kinase activity | protein modification by small protein conjugation or removal | skin epidermis development | regulation of phosphate metabolic process | cytoskeleton organization | cell-cell adhesion | response to interferon-gamma | positive regulation of intracellular transport | regulation of JNK cascade | regulation of hair follicle cell proliferation | positive regulation of MAPK cascade | positive regulation of protein transport | regulation of peptidyl-serine phosphorylation | dendrite morphogenesis | anatomical structure formation involved in morphogenesis | regulation of stress fiber assembly | establishment of apical/basal cell polarity | regulation of stress-activated MAPK cascade | regulation of cell communication | signaling | positive regulation of growth | regulation of protein binding | cell development | neuron fate determination | protein localization | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | anatomical structure morphogenesis | cellular macromolecule localization | regulation of actin filament bundle assembly | positive regulation of plasma membrane bounded cell projection assembly | dendrite development | regulation of developmental process | regulation of pseudopodium assembly | positive regulation of DNA metabolic process | developmental process | organelle organization | positive regulation of cell cycle process | regulation of cell growth | cellular protein modification process | tube development | regulation of transport | innate immune response | Ras protein signal transduction | cell fate determination | regulation of lamellipodium assembly | positive regulation of lipid kinase activity | epithelial cell differentiation | establishment of Golgi localization | regulation of lipid metabolic process | positive regulation of metabolic process | regulation of actin filament-based process | positive regulation of lipid metabolic process | regulation of cell projection organization | immune system process | cellular metabolic process | cellular response to organic substance | regulation of protein localization | exocrine system development | regulation of cell death | regulation of substrate adhesion-dependent cell spreading | response to carbohydrate | salivary gland development | establishment of epithelial cell apical/basal polarity | positive regulation of cell morphogenesis involved in differentiation | neuropilin signaling pathway | circulatory system development | phagocytosis | positive regulation of substrate adhesion-dependent cell spreading | regulation of cellular component organization | regulation of cytoskeleton organization | positive regulation of signaling | hair follicle development | positive regulation of epithelial cell proliferation involved in lung morphogenesis | signal transduction | regulation of signaling | viral RNA genome replication | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
secretory granule | dendritic spine | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | organelle membrane | cell projection membrane | microtubule organizing center | cytoplasmic vesicle | cell body | actin-based cell projection | cell | neuronal cell body | ribonucleoprotein granule | Golgi transport complex | tethering complex | lamellipodium | cytoplasm | spindle | intracellular organelle | dendritic tree | leading edge membrane | apical part of cell | centrosome | cell-cell junction | Golgi apparatus | protein-containing complex | cell projection | secretory vesicle | endomembrane system | neuron spine | postsynapse | plasma membrane | midbody | cell leading edge | vacuole | ribonucleoprotein complex | vesicle | microtubule cytoskeleton | cytoplasmic region | spindle midzone | Golgi membrane | cell cortex | membrane-bounded organelle | filopodium | organelle | cytoplasmic ribonucleoprotein granule | cell periphery | cytosol | storage vacuole | intracellular vesicle | cytoskeleton | endocytic vesicle | intracellular | cell junction | myelin sheath | mitotic spindle | membrane | lamellipodium membrane | phagocytic vesicle
