QuickView for EPM2A;jsessionid=38C34630750D77C03B572E4444C764D0;jsessionid=DC9359B25CE6FF76F8D05C80C02C4EAC (gene)
- Gene Symbol:
- Epm2a
Rattus norvegicus - Full name:
- EPM2A, laforin glucan phosphatase
- Synonyms:
- laforin, LAFPTPase, epilepsy, progressive myoclonic epilepsy, type 2 gene alpha, epilepsy, progressive myoclonus type 2A, glucan phosphatase, lafora PTPase
- Genomic Location:
- N/A
- Description:
-
encodes a dual-specificity phosphatase (DSP) named laforin
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
protein serine/threonine phosphatase activity | phosphatase activity | protein tyrosine/serine/threonine phosphatase activity | hydrolase activity | protein tyrosine phosphatase activity | catalytic activity | phosphoprotein phosphatase activity | glycogen binding | hydrolase activity, acting on ester bonds | identical protein binding | carbohydrate binding | protein binding | protein homodimerization activity | protein dimerization activity | phosphoric ester hydrolase activity | starch binding | carbohydrate phosphatase activity | polysaccharide binding
GO Biological Process
protein serine/threonine phosphatase activity | negative regulation of TOR signaling | regulation of dephosphorylation | protein dephosphorylation | regulation of autophagy | negative regulation of cellular process | regulation of phosphatase activity | nervous system development | generation of precursor metabolites and energy | cellular process | negative regulation of signaling | habituation | learning | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | phosphorylated carbohydrate dephosphorylation | negative regulation of phosphatase activity | phosphatase activity | protein tyrosine/serine/threonine phosphatase activity | cellular polysaccharide metabolic process | polysaccharide metabolic process | regulation of macroautophagy | negative regulation of metabolic process | protein modification process | macromolecule modification | regulation of TOR signaling | protein tyrosine phosphatase activity | system development | glycogen metabolic process | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | phosphorus metabolic process | learning or memory | regulation of catalytic activity | nonassociative learning | nervous system process | positive regulation of cellular metabolic process | phosphoprotein phosphatase activity | cellular carbohydrate metabolic process | cognition | carbohydrate metabolic process | phosphate-containing compound metabolic process | autophagy | regulation of cellular metabolic process | protein metabolic process | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | metabolic process | oxidation-reduction process | behavior | organic substance metabolic process | regulation of phosphate metabolic process | positive regulation of autophagy | positive regulation of macroautophagy | regulation of cell communication | dephosphorylation | negative regulation of molecular function | negative regulation of signal transduction | energy reserve metabolic process | cellular protein metabolic process | energy derivation by oxidation of organic compounds | developmental process | cellular glucan metabolic process | cellular protein modification process | peptidyl-tyrosine dephosphorylation | negative regulation of dephosphorylation | negative regulation of hydrolase activity | positive regulation of metabolic process | cellular metabolic process | carbohydrate phosphatase activity | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
cytoplasmic side of rough endoplasmic reticulum membrane | rough endoplasmic reticulum membrane | intracellular membrane-bounded organelle | polysome | organelle membrane | cell | cytoplasmic side of membrane | nuclear lumen | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | nucleoplasm | plasma membrane | cytoplasmic side of endoplasmic reticulum membrane | ribonucleoprotein complex | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | rough endoplasmic reticulum | cytosol | intracellular | membrane
