QuickView for GABRG2;jsessionid=D24A07D508B2F41E843893B422CBB34A;jsessionid=4CDFFBD02504603915EBAD2104F73ADB (gene)

Gene Symbol:

Gabrg2 Mus musculus

Full name:

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

Synonyms:

GABAA-R, Gabrg-2, gamma2, gamma-aminobutyric acid receptor subunit gamma-2

Genomic Location:

Chr 11: 41723697-41814180

Description:

This gene encodes a gamma-aminobutyric acid (GABA)-A receptor subunit, which is a member of the ligand-gated ion channel family. GABA is the major inhibitory neurotransmitter in the adult central nervous system, and conversely exhibits an excitatory function during development. GABA-A receptors are pentameric, consisting of proteins from several su...

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This gene encodes a gamma-aminobutyric acid (GABA)-A receptor subunit, which is a member of the ligand-gated ion channel family. GABA is the major inhibitory neurotransmitter in the adult central nervous system, and conversely exhibits an excitatory function during development. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. This gene encodes one of three gamma subunits in mammals, which contain the binding site for benzodiazepine drugs. Several mutations in this gene are associated with epileptic seizures, and genetic knockdown is associated with anxiety behavior. Alternative splicing results in multiple transcript variants.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E47_01 ,  GATA1_03 ,  OCT1_02 ,  OCT1_04 ,  CAGNWMCNNNGAC_UNKNOWN ,  NRSF_01 ,  PAX8_B ,  WHN_B ,  MEIS1BHOXA9_01 ,  ZIC1_01 ,  ZIC2_01 ,  ZIC3_01 ,  POU3F2_02 ,  LFA1_Q6 ,  ATF1_Q6 ,  LEF1_Q6 ,  PPAR_DR1_Q2 ,  EGR_Q6 ,  ER_Q6_02 ,  ATGCTGC_MIR103_MIR107 ,  TTGGGAG_MIR150 ,  ATGTACA_MIR493 ,  RTTTNNNYTGGM_UNKNOWN ,  YNGTTNNNATT_UNKNOWN ,  CAGGTG_E12_Q6 ,  TGACCTY_ERR1_Q2 ,  TTGTTT_FOXO4_01 ,  CTTTGA_LEF1_Q2 ,  CTTTGT_LEF1_Q2 ,  GGGAGGRR_MAZ_Q6 ,  GGGTGGRR_PAX4_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-150 ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-496

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