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QuickView for GSTO1;jsessionid=30E65F6270F457B55414F11DF7A2BA89;jsessionid=6438AF8BE013D4FDD76AE0AB37B44ABB (gene)


Gene Symbol:
Gsto1 Mus musculus Mus musculus
Full name:
glutathione S-transferase omega 1
Synonyms:
AA407097, AI194287, AU018802, Gsto-1, Gstx, Spg-r, p28, glutathione S-transferase omega-1, Glutathione transferase omega 1 (GSTO 1-1) (p28), MMA(V) reductase, S-(Phenacyl)glutathione reductase, glutathione S-transferase omega 1-1, glutathione-S-transferase like, glutathione-dependent dehydroascorbate reductase, monomethylarsonic acid reductase
Genomic Location:
Chr 19: 47929479-47939280
Description:
This gene encodes a member of the omega class of glutathione S-transferase (GST) proteins. GSTs are involved in the metabolism of xenobiotics and carcinogens. There is evidence that the encoded protein is involved in the biotransformation of arsenic.
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene


Transcripts Names
NM_010362
Protein Names
O09131
Q3TH87



GO Molecular Function

glutathione transferase activity | antioxidant activity | transferase activity, transferring alkyl or aryl (other than methyl) groups | catalytic activity | glutathione dehydrogenase (ascorbate) activity | oxidoreductase activity, acting on a sulfur group of donors | glutathione disulfide oxidoreductase activity | disulfide oxidoreductase activity | methylarsonate reductase activity | transferase activity | peptide disulfide oxidoreductase activity | oxidoreductase activity

GO Biological Process

positive regulation of release of sequestered calcium ion into cytosol | positive regulation of ion transmembrane transporter activity | regulation of cellular localization | vitamin biosynthetic process | regulation of localization | negative regulation of cellular process | cellular chemical homeostasis | xenobiotic catabolic process | positive regulation of cation channel activity | cellular process | cellular homeostasis | cellular detoxification | regulation of calcium-mediated signaling | antioxidant activity | negative regulation of signaling | regulation of cellular process | xenobiotic metabolic process | positive regulation of ryanodine-sensitive calcium-release channel activity | catabolic process | regulation of cytosolic calcium ion concentration | negative regulation of calcium-mediated signaling | calcium ion homeostasis | response to stimulus | cellular response to xenobiotic stimulus | positive regulation of cation transmembrane transport | L-ascorbic acid biosynthetic process | negative regulation of transporter activity | cellular response to toxic substance | negative regulation of transport | cofactor metabolic process | cellular biosynthetic process | negative regulation of calcium ion transmembrane transport | negative regulation of transmembrane transport | metal ion homeostasis | regulation of calcium ion transport into cytosol | regulation of signal transduction | coenzyme biosynthetic process | positive regulation of calcium ion transmembrane transport | glutathione dehydrogenase (ascorbate) activity | oxidoreductase activity, acting on a sulfur group of donors | cellular ion homeostasis | cofactor biosynthetic process | glutathione disulfide oxidoreductase activity | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | monosaccharide metabolic process | small molecule metabolic process | negative regulation of release of sequestered calcium ion into cytosol | positive regulation of intracellular signal transduction | positive regulation of calcium-mediated signaling | regulation of release of sequestered calcium ion into cytosol | negative regulation of ion transmembrane transport | carbohydrate biosynthetic process | negative regulation of calcium ion transmembrane transporter activity | biosynthetic process | negative regulation of ion transport | carbohydrate metabolic process | regulation of calcium ion transmembrane transport | response to toxic substance | response to xenobiotic stimulus | cation homeostasis | cellular cation homeostasis | L-ascorbic acid metabolic process | negative regulation of cation channel activity | positive regulation of transporter activity | positive regulation of sequestering of calcium ion | negative regulation of calcium ion transport | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | positive regulation of transport | negative regulation of calcium ion transport into cytosol | disulfide oxidoreductase activity | carboxylic acid metabolic process | positive regulation of molecular function | regulation of ryanodine-sensitive calcium-release channel activity | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | methylarsonate reductase activity | vitamin metabolic process | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | metabolic process | cellular response to arsenic-containing substance | cellular oxidant detoxification | oxidation-reduction process | chemical homeostasis | negative regulation of ion transmembrane transporter activity | organic substance metabolic process | regulation of sequestering of calcium ion | positive regulation of ion transport | ion homeostasis | regulation of ion transmembrane transport | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | response to arsenic-containing substance | positive regulation of calcium ion transmembrane transporter activity | regulation of transmembrane transporter activity | organic acid metabolic process | regulation of ion transmembrane transporter activity | positive regulation of calcium ion transport into cytosol | regulation of ion transport | peptide disulfide oxidoreductase activity | negative regulation of ryanodine-sensitive calcium-release channel activity | regulation of calcium ion transport | regulation of transport | detoxification | regulation of cation channel activity | cellular metal ion homeostasis | regulation of calcium ion transmembrane transporter activity | cellular metabolic process | oxidoreductase activity | divalent inorganic cation homeostasis | positive regulation of calcium ion transport | positive regulation of signaling | regulation of signaling

GO Cellular Component

intracellular membrane-bounded organelle | neuron projection | extracellular matrix | basement membrane | organelle membrane | nuclear membrane | cell body | cell | cytoplasm | collagen-containing extracellular matrix | intracellular organelle | cell projection | endomembrane system | nuclear envelope | extracellular region | membrane-bounded organelle | nucleus | organelle | axon | cytosol | intracellular | myelin sheath | membrane