QuickView for HDAC8;jsessionid=F949DE42DBAA5C59033927D316DDCF25;jsessionid=406D52A25524EBCC736D6C5CFA0FA5A0 (gene)
- Gene Symbol:
- Hdac8
Rattus norvegicus - Full name:
- histone deacetylase 8
- Synonyms:
- HD8, RGD1562895, histone deacetylase 8
- Genomic Location:
- Chr X: 90336001-90544474
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
| Transcripts Names |
|---|
| XM_343804 |
| XM_001070606 |
| NM_001126373 |
| XM_017602109 |
| XM_008773263 |
| XM_006257123 |
| XR_001842614 |
GO Molecular Function
cation binding | histone deacetylase activity (H3-K14 specific) | NAD-dependent histone deacetylase activity (H3-K14 specific) | hydrolase activity | protein deacetylase activity | catalytic activity | chromatin binding | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | Hsp70 protein binding | NAD-dependent protein deacetylase activity | histone deacetylase activity | ion binding | NAD-dependent histone deacetylase activity | protein binding | transcription factor binding | Hsp90 protein binding | deacetylase activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | heat shock protein binding | metal ion binding
GO Biological Process
RNA metabolic process | regulation of cell cycle process | regulation of cellular localization | regulation of localization | negative regulation of cellular process | histone modification | response to drug | histone deacetylation | regulation of organelle organization | response to antibiotic | regulation of chromosome segregation | cellular process | chromatin organization | regulation of histone modification | regulation of cell cycle | histone deacetylase activity (H3-K14 specific) | negative regulation of peptidyl-lysine acetylation | negative regulation of cellular metabolic process | regulation of binding | regulation of histone H3-K9 acetylation | regulation of cell differentiation | regulation of cellular process | regulation of osteoblast differentiation | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | regulation of cellular protein localization | chromosome segregation | NAD-dependent histone deacetylase activity (H3-K14 specific) | cellular nitrogen compound biosynthetic process | regulation of protein ubiquitination | response to alcohol | cellular nitrogen compound metabolic process | regulation of DNA binding | cellular response to organic cyclic compound | negative regulation of metabolic process | protein modification process | protein deacetylase activity | cellular biosynthetic process | macromolecule modification | histone H3 deacetylation | cellular response to forskolin | regulation of nucleic acid-templated transcription | response to nitrogen compound | negative regulation of osteoblast differentiation | nitrogen compound metabolic process | regulation of protein stability | cellular response to antibiotic | NAD-dependent protein deacetylase activity | sister chromatid segregation | regulation of telomere maintenance | regulation of ossification | regulation of gene expression | histone deacetylase activity | response to ketone | response to lipid | cell cycle | regulation of nitrogen compound metabolic process | regulation of cohesin loading | biosynthetic process | protein deacetylation | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | NAD-dependent histone deacetylase activity | cellular response to drug | nuclear chromosome segregation | regulation of cellular metabolic process | regulation of protein metabolic process | negative regulation of histone H3-K9 acetylation | regulation of RNA metabolic process | negative regulation of protein ubiquitination | regulation of sister chromatid cohesion | protein metabolic process | response to organic substance | negative regulation of ossification | regulation of sister chromatid segregation | metabolic process | regulation of RNA biosynthetic process | negative regulation of histone acetylation | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | gene expression | regulation of chromosome organization | transcription, DNA-templated | regulation of protein localization to chromatin | negative regulation of protein metabolic process | negative regulation of chromosome organization | covalent chromatin modification | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular protein metabolic process | cellular macromolecule biosynthetic process | regulation of developmental process | organelle organization | sister chromatid cohesion | cellular protein modification process | cellular response to trichostatin A | regulation of histone acetylation | negative regulation of protein acetylation | response to organonitrogen compound | heterocycle metabolic process | chromosome organization | cellular metabolic process | cellular response to organic substance | regulation of protein localization | negative regulation of cell differentiation | regulation of cellular component organization | macromolecule metabolic process | regulation of chromatin organization
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | intracellular | membrane
