QuickView for Idh1;jsessionid=2999DD2F247A6EE6AA0BE90107732467;jsessionid=9DD19B710173F2CFCE855E5B85A0E88F;jsessionid=4F6A1697844A792B8C89E7B2A95C9A08;jsessionid=79D8E3393535B2B3466212F4BE5B6F3B (gene)
- Gene Symbol:
- Idh1
Rattus norvegicus - Full name:
- isocitrate dehydrogenase (NADP(+)) 1, cytosolic
- Synonyms:
- isocitrate dehydrogenase [NADP] cytoplasmic, IDH, IDP, Isocitrate dehydrogenase 1, soluble, NADP(+)-specific ICDH, cytosolic NADP-isocitrate dehydrogenase, isocitrate dehydrogenase 1 (NADP+), soluble, oxalosuccinate decarboxylase
- Genomic Location:
- Chr 9: 63769401-63790622
- Description:
-
catalyzes oxidative decarboxylation of citrate; cytosolic NADP+-dependent isozyme
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Schizosaccharomyces pombe , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
oxidoreductase activity, acting on CH-OH group of donors | NADP binding | cofactor binding | cation binding | magnesium ion binding | isocitrate dehydrogenase activity | nucleotide binding | coenzyme binding | signaling receptor binding | catalytic activity | identical protein binding | ion binding | organic cyclic compound binding | protein binding | protein homodimerization activity | (R)-2-hydroxyglutarate dehydrogenase activity | NAD binding | protein dimerization activity | isocitrate dehydrogenase (NADP+) activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | metal ion binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
oxidoreductase activity, acting on CH-OH group of donors | tricarboxylic acid cycle | developmental process involved in reproduction | sulfur compound metabolic process | gonad development | female gonad development | glutathione metabolic process | response to hormone | generation of precursor metabolites and energy | aerobic respiration | cellular process | dicarboxylic acid metabolic process | nucleotide metabolic process | reproductive system development | cellular respiration | isocitrate dehydrogenase activity | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | development of primary sexual characteristics | response to stimulus | monocarboxylic acid metabolic process | response to stress | development of primary female sexual characteristics | reproduction | cellular nitrogen compound metabolic process | cofactor metabolic process | glyoxylate metabolic process | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | antibiotic metabolic process | phosphorus metabolic process | regulation of phospholipid biosynthetic process | response to lipid | organophosphate metabolic process | regulation of phospholipid catabolic process | small molecule metabolic process | cellular carbohydrate metabolic process | cellular amide metabolic process | response to oxidative stress | nucleobase-containing small molecule metabolic process | carbohydrate metabolic process | phosphate-containing compound metabolic process | regulation of cellular metabolic process | 2-oxoglutarate metabolic process | regulation of lipid catabolic process | peptide metabolic process | regulation of phospholipid metabolic process | regulation of lipid biosynthetic process | drug metabolic process | carboxylic acid metabolic process | cellular aldehyde metabolic process | response to organic substance | (R)-2-hydroxyglutarate dehydrogenase activity | tricarboxylic acid metabolic process | anatomical structure development | metabolic process | isocitrate dehydrogenase (NADP+) activity | oxidation-reduction process | citrate metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | regulation of phosphate metabolic process | glyoxylate cycle | isocitrate metabolic process | response to organic cyclic compound | organic acid metabolic process | NADP metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | reproductive structure development | energy derivation by oxidation of organic compounds | developmental process | nicotinamide nucleotide metabolic process | cellular modified amino acid metabolic process | heterocycle metabolic process | regulation of lipid metabolic process | cellular metabolic process | female sex differentiation | sex differentiation | oxidoreductase activity | response to steroid hormone | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | peroxisome | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | cytosol | intracellular
