QuickView for JJJ1;jsessionid=934C9D4EAB0C70903BB3066CC1964E3D;jsessionid=79A2FE3CBA013E759D5346CADF4CA647;jsessionid=FB7667FA84C200E78E158C9E918F7634;jsessionid=65B66A10C3F8834F3ECDC5D3722DE542;jsessionid=59CA00FC956778A007D40F9E13127A75 (gene)

Gene Symbol:

DNAJC21 Homo sapiens

Full name:

DnaJ heat shock protein family (Hsp40) member C21

Synonyms:

BMFS3, DNAJA5, GS3, JJJ1, dnaJ homolog subfamily C member 21, DnaJ (Hsp40) homolog, subfamily C, member 21, DnaJ homology subfamily A member 5, JJJ1 DnaJ domain protein homolog, dnaJ homolog subfamily A member 5

Genomic Location:

Chr 5: 34965455-34994826

Description:

This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the precursor 45S ribosomal RNA and may be involved in early nuclear ribosomal RNA biogenesis and maturation of the 60S ribosomal subunit. Mutations...

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This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the precursor 45S ribosomal RNA and may be involved in early nuclear ribosomal RNA biogenesis and maturation of the 60S ribosomal subunit. Mutations in this gene result in Bone marrow failure syndrome 3. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  ATGTACA_MIR493 ,  GTACAGG_MIR486 ,  CATTTCA_MIR203 ,  CTTTAAR_UNKNOWN ,  CTCTAGA_MIR526C_MIR518F_MIR526A ,  GTTNYYNNGGTNA_UNKNOWN

Cytogenetic Map:

5p13.2

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