QuickView for LC3;jsessionid=832AF50DE561E3C8AC8B02B8774F8934;jsessionid=EB3B94F8258E70127A4590854CDA504C (gene)

Gene Symbol:

MAP1LC3A Homo sapiens

Full name:

microtubule associated protein 1 light chain 3 alpha

Synonyms:

ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, microtubule-associated proteins 1A/1B light chain 3A, MAP1 light chain 3-like protein 1, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1A/MAP1B light chain 3 A, autophagy-related ubiquitin-like modifier LC3 A, microtubule-associated proteins 1A/1B light chain 3

Genomic Location:

Chr 20: 32598353-32611810

Description:

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B...

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MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CREBP1CJUN_01 ,  CREB_Q4_01 ,  MZF1_01 ,  AML_Q6 ,  ATF4_Q2 ,  AP2ALPHA_01 ,  CREB_Q4 ,  OSF2_Q6 ,  TGAYRTCA_ATF3_Q6 ,  ATF_B ,  CREBP1_Q2 ,  GTGACGY_E4F1_Q6 ,  ATF_01 ,  P53_02 ,  CREB_02 ,  ATF3_Q6 ,  E4F1_Q6 ,  CTTTAAR_UNKNOWN ,  RACCACAR_AML_Q6 ,  ATF1_Q6 ,  CREB_Q2 ,  IK3_01 ,  TGACGTCA_ATF3_Q6 ,  ER_Q6_02 ,  ER_Q6_01 ,  ER_Q6 ,  DR4_Q2 ,  COREBINDINGFACTOR_Q6 ,  CREB_Q2_01 ,  CREB_01 ,  GGGTGGRR_PAX4_03 ,  TAXCREB_01 ,  OLF1_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-544

Cytogenetic Map:

20q11.22

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