QuickView for NEDD4;jsessionid=B516AB549947C0E8EE4A661E64F0EC3B;jsessionid=64554C3D1DED733E51A3986071A67120;jsessionid=FBBA7350AE305E1421E6D80E95EDCD66;jsessionid=5E59B1A2424366FF326346869455F2F1 (gene)
- Gene Symbol:
- Nedd4
Mus musculus - Full name:
- neural precursor cell expressed, developmentally down-regulated 4
- Synonyms:
- AA959633, AL023035, AU019897, E430025J12Rik, EG639396, Gm7265, KIAA0093, Nedd4-1, Nedd4a, E3 ubiquitin-protein ligase NEDD4, HECT-type E3 ubiquitin transferase NEDD4, neural precursor cell expressed developmentally down-regulated protein 4, neural precursor cell expressed, developmentally down-regulated gene 4a
- Genomic Location:
- Chr 9: 72510154-72597655
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Pan troglodytes , Bos taurus , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
protein phosphorylated amino acid binding | sodium channel inhibitor activity | channel regulator activity | phosphoserine residue binding | sodium channel regulator activity | ion channel inhibitor activity | signaling receptor binding | molecular function regulator | catalytic activity | channel inhibitor activity | ubiquitin-like protein transferase activity | proline-rich region binding | ubiquitin protein ligase activity | phosphoprotein binding | protein binding | ubiquitin-protein transferase activity | transferase activity | ubiquitin-like protein ligase activity | phosphothreonine residue binding | protein C-terminus binding | glutamate receptor binding | ionotropic glutamate receptor binding
GO Biological Process
adaptive immune response | regulation of cell morphogenesis | regulation of neurogenesis | regulation of sodium ion transmembrane transporter activity | proteolysis | regulation of cell development | protein localization to vacuole | regulation of localization | sodium channel inhibitor activity | regulation of sodium ion transport | establishment of localization | negative regulation of cellular process | negative regulation of RNA biosynthetic process | cell differentiation | nervous system development | positive regulation of protein catabolic process | neurogenesis | generation of neurons | mesenchyme development | intracellular transport | blood vessel morphogenesis | cellular process | protein K63-linked ubiquitination | organic substance catabolic process | channel regulator activity | localization | proteolysis involved in cellular protein catabolic process | protein transport | heart morphogenesis | regulation of sodium ion transmembrane transport | negative regulation of signaling | neuron development | regulation of vascular endothelial growth factor receptor signaling pathway | negative regulation of nucleic acid-templated transcription | macromolecule localization | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | establishment of localization in cell | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | regulation of cellular process | sodium channel regulator activity | leukocyte activation | regulation of metabolic process | catabolic process | cellular component organization | T cell activation | response to stimulus | negative regulation of vascular endothelial growth factor receptor signaling pathway | lysosomal transport | vasculature development | ion channel inhibitor activity | protein targeting to lysosome | positive regulation of protein metabolic process | intracellular protein transport | vacuolar transport | tube morphogenesis | negative regulation of transporter activity | cellular protein catabolic process | cellular localization | cardiovascular system development | proteasomal protein catabolic process | negative regulation of transport | negative regulation of metabolic process | protein modification process | regulation of synapse structure or activity | macromolecule modification | negative regulation of transmembrane transport | molecular function regulator | protein targeting to vacuole | blood vessel development | regulation of nucleic acid-templated transcription | endocardial cushion development | system development | nitrogen compound metabolic process | regulation of signal transduction | protein monoubiquitination | channel inhibitor activity | multicellular organism development | protein localization to lysosome | negative regulation of sodium ion transmembrane transporter activity | regulation of neuron differentiation | regulation of gene expression | outflow tract morphogenesis | organic substance transport | protein catabolic process | neuromuscular junction development | animal organ morphogenesis | regulation of synapse organization | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | peptide transport | negative regulation of cellular response to growth factor stimulus | vesicle-mediated transport | regulation of transcription by RNA polymerase II | ubiquitin protein ligase activity | synapse organization | protein localization to organelle | negative regulation of ion transmembrane transport | negative regulation of ion transport | regulation of cellular metabolic process | receptor internalization | regulation of protein metabolic process | heart development | regulation of RNA metabolic process | regulation of cellular response to growth factor stimulus | proteasome-mediated ubiquitin-dependent protein catabolic process | lymphocyte activation | protein polyubiquitination | neuron differentiation | regulation of cell morphogenesis involved in differentiation | protein metabolic process | receptor catabolic process | protein ubiquitination | import into cell | cellular macromolecule catabolic process | establishment of protein localization to organelle | anatomical structure development | regulation of dendrite morphogenesis | cell projection organization | metabolic process | ubiquitin-protein transferase activity | regulation of protein catabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | cellular protein localization | amide transport | endocytosis | immune response | neuron projection development | negative regulation of ion transmembrane transporter activity | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | negative regulation of sodium ion transmembrane transport | protein modification by small protein conjugation or removal | establishment of protein localization to vacuole | regulation of ion transmembrane transport | establishment of protein localization | cell activation | ubiquitin-dependent protein catabolic process | regulation of dendrite development | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | regulation of transcription, DNA-templated | cell development | regulation of transmembrane transporter activity | protein localization | regulation of ion transmembrane transporter activity | cellular protein metabolic process | anatomical structure morphogenesis | cellular macromolecule localization | regulation of nervous system development | regulation of developmental process | regulation of ion transport | receptor-mediated endocytosis | developmental process | cellular protein modification process | negative regulation of transcription by RNA polymerase II | tube development | regulation of transport | receptor metabolic process | positive regulation of metabolic process | protein targeting | negative regulation of sodium ion transport | regulation of cell projection organization | immune system process | cellular metabolic process | modification-dependent protein catabolic process | circulatory system development | regulation of cellular component organization | regulation of signaling | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
dendritic spine | dendrite | synapse | catalytic complex | neuron projection | somatodendritic compartment | actin-based cell projection | cell | cytoplasm | membrane microdomain | ubiquitin ligase complex | dendritic tree | protein-containing complex | cell projection | neuron spine | postsynapse | plasma membrane | membrane raft | transferase complex | microvillus | cell periphery | cytosol | intracellular | membrane
