QuickView for Nestin;jsessionid=2191B6F1A4162BA01EB4E99AC8438C93;jsessionid=167393C04EFF6C70E26C119A406784B0 (gene)
- Gene Symbol:
- Nes
Rattus norvegicus - Full name:
- nestin
- Synonyms:
- nestin
- Genomic Location:
- Chr 2: 180051907-180060947
- Description:
-
intermediate filament protein specifically expressed in neuroepithelial stem cells; may play a role in neural cell differentiation
- Orthologs:
- Homo sapiens , Mus musculus , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
structural molecule activity | CCR chemokine receptor binding | protein-containing complex binding | signaling receptor binding | cytokine receptor binding | chemokine receptor binding | protein binding | G-protein coupled receptor binding | intermediate filament binding | CCR5 chemokine receptor binding
GO Biological Process
response to extracellular stimulus | brain development | response to radiation | cell morphogenesis | response to nutrient levels | positive regulation of cellular component organization | regulation of programmed cell death | eye development | negative regulation of neuron death | negative regulation of cellular process | cell differentiation | nervous system development | response to drug | cell part morphogenesis | neurogenesis | regulation of organelle organization | generation of neurons | regulation of neuron death | cellular process | cell projection morphogenesis | negative regulation of apoptotic process | regulation of binding | regulation of cellular process | regulation of apoptotic process | positive regulation of protein complex disassembly | cellular component organization | head development | response to stimulus | regulation of cell proliferation | positive regulation of intermediate filament depolymerization | embryo development | negative regulation of neuron apoptotic process | system development | positive regulation of organelle organization | multicellular organism development | negative regulation of catalytic activity | regulation of catalytic activity | regulation of protein complex disassembly | stem cell proliferation | cell cycle | positive regulation of protein depolymerization | negative regulation of binding | embryonic camera-type eye development | cell proliferation | G2/M transition of mitotic cell cycle | mitotic cell cycle phase transition | sensory organ development | negative regulation of protein binding | regulation of neuron apoptotic process | positive regulation of cytoskeleton organization | cell cycle G2/M phase transition | positive regulation of cell proliferation | regulation of protein depolymerization | neuron differentiation | anatomical structure development | mitotic cell cycle | regulation of neural precursor cell proliferation | cell projection organization | negative regulation of programmed cell death | embryonic organ development | regulation of intermediate filament polymerization or depolymerization | animal organ development | camera-type eye development | negative regulation of molecular function | regulation of protein binding | anatomical structure morphogenesis | positive regulation of neural precursor cell proliferation | developmental process | cell cycle phase transition | central nervous system development | regulation of cell death | negative regulation of cell death | regulation of cellular component organization | response to ionizing radiation | regulation of cytoskeleton organization | multicellular organismal process
GO Cellular Component
intermediate filament | supramolecular fiber | cell | cytoplasm | intracellular organelle | intermediate filament cytoskeleton | organelle | cytoskeleton | intracellular | supramolecular complex
