QuickView for PLAT;jsessionid=E20746CCE46830A7EF5877E8C390BEBA;jsessionid=21F50D2DB630FC75898DAD3DB1A034DF (gene)
- Gene Symbol:
- Plat
Rattus norvegicus - Full name:
- plasminogen activator, tissue type
- Synonyms:
- PATISS, tPA, tissue-type plasminogen activator, t-PA, t-plasminogen activator, tissue plasminogen activator
- Genomic Location:
- Chr 16: 73711323-73736304
- Description:
-
serine protease; catalyzes conversion of inactive proenzyme plasminogen into active serine protease plasmin
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
signaling receptor binding | hydrolase activity | catalytic activity | serine hydrolase activity | phosphoprotein binding | protein binding | serine-type endopeptidase activity | serine-type peptidase activity | endopeptidase activity | peptidase activity
GO Biological Process
cellular response to luteinizing hormone stimulus | cell motility | proteolysis | response to luteinizing hormone | response to hormone | negative regulation of cellular process | protein processing | response to dexamethasone | response to drug | negative regulation of proteolysis | response to organophosphorus | cellular process | localization | zymogen activation | chemical synaptic transmission | response to hypoxia | regulation of proteolysis | negative regulation of cellular metabolic process | response to peptide hormone | regulation of cellular process | cellular response to lipid | regulation of metabolic process | cellular response to organonitrogen compound | response to stimulus | cellular response to xenobiotic stimulus | response to stress | response to peptide | cellular response to organic cyclic compound | negative regulation of metabolic process | modulation of chemical synaptic transmission | cell-cell signaling | locomotion | response to nitrogen compound | cellular response to hormone stimulus | response to oxygen levels | nitrogen compound metabolic process | cell migration | cellular response to peptide hormone stimulus | response to purine-containing compound | response to follicle-stimulating hormone | response to fatty acid | wound healing | platelet-derived growth factor receptor signaling pathway | response to ketone | response to lipid | cellular response to peptide | synaptic signaling | cellular response to gonadotropin stimulus | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | response to corticosteroid | synaptic transmission, glutamatergic | regulation of cellular protein metabolic process | cellular response to glucocorticoid stimulus | protein maturation | response to xenobiotic stimulus | cellular response to corticosteroid stimulus | positive regulation of ovulation | cellular response to drug | cell communication | regulation of cellular metabolic process | smooth muscle cell migration | regulation of protein metabolic process | protein metabolic process | muscle cell migration | response to organic substance | response to wounding | response to antineoplastic agent | cell surface receptor signaling pathway | metabolic process | organic substance metabolic process | regulation of ovulation | negative regulation of cellular protein metabolic process | gene expression | serine-type endopeptidase activity | cellular response to steroid hormone stimulus | serine-type peptidase activity | response to gonadotropin | response to cAMP | cellular response to follicle-stimulating hormone stimulus | cellular response to dexamethasone stimulus | negative regulation of protein metabolic process | regulation of cell communication | signaling | response to organic cyclic compound | endopeptidase activity | response to organonitrogen compound | plasminogen activation | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of synaptic plasticity | peptidase activity | cellular response to organic substance | response to steroid hormone | signal transduction | regulation of signaling | response to glucocorticoid | macromolecule metabolic process
GO Cellular Component
secretory granule | synapse | extracellular matrix | cytoplasmic vesicle | cell | cytoplasm | collagen-containing extracellular matrix | intracellular organelle | apical part of cell | secretory vesicle | endomembrane system | vesicle | extracellular region | membrane-bounded organelle | organelle | extracellular space | intracellular vesicle | cell surface | intracellular
