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QuickView for PRKCA;jsessionid=9840EA03F7C5B5AFAF8D8769FEB9FCFD;jsessionid=C991265958E1304BBBD9681F1E422331 (gene)


Gene Symbol:
PRKCA Bos taurus Bos taurus
Full name:
protein kinase C, alpha
Synonyms:
PKRCA
Genomic Location:
Chr 19: 64375604-64669475
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_174435
Protein Names
P04409



GO Molecular Function

histone threonine kinase activity | cation binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | protein kinase C activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | scaffold protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | zinc ion binding | histone kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | transition metal ion binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | histone kinase activity (H3-T6 specific) | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

regulation of ERK1 and ERK2 cascade | regulation of muscle system process | positive regulation of locomotion | histone threonine kinase activity | response to cytokine | response to interleukin-1 | intracellular signal transduction | regulation of localization | regulation of programmed cell death | peptidyl-amino acid modification | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | histone modification | positive regulation of epithelial cell proliferation | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | blood vessel morphogenesis | cellular process | regulation of cell motility | chromatin organization | regulation of platelet aggregation | negative regulation of apoptotic process | regulation of cell cycle | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | positive regulation of cardiac muscle hypertrophy | cell junction assembly | regulation of platelet activation | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular component organization | positive regulation of epithelial cell migration | regulation of vasculature development | response to stimulus | peptidyl-threonine phosphorylation | vasculature development | positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway | positive regulation of immune system process | positive regulation of protein metabolic process | regulation of cell proliferation | tube morphogenesis | protein serine/threonine kinase activity | programmed cell death | protein kinase C activity | cardiovascular system development | positive regulation of blood vessel endothelial cell migration | cellular component assembly | regulation of wound healing | protein modification process | regulation of cell adhesion | macromolecule modification | blood vessel development | positive regulation of macrophage differentiation | apoptotic process | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | regulation of MAPK cascade | phosphorus metabolic process | regulation of phosphorylation | positive regulation of cell cycle | positive regulation of mitotic cell cycle | positive regulation of dense core granule biogenesis | desmosome assembly | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of blood coagulation | regulation of nitrogen compound metabolic process | regulation of cell migration | positive regulation of intracellular signal transduction | regulation of cellular component movement | positive regulation of cell differentiation | regulation of endothelial cell migration | positive regulation of myeloid cell differentiation | positive regulation of cell migration | regulation of cellular protein metabolic process | histone H3-T6 phosphorylation | angiogenesis | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of cAMP-mediated signaling | desmosome organization | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | histone phosphorylation | regulation of mitotic cell cycle | protein metabolic process | regulation of cardiac muscle hypertrophy | positive regulation of protein modification process | response to organic substance | regulation of homotypic cell-cell adhesion | regulation of hemopoiesis | histone kinase activity | regulation of lipopolysaccharide-mediated signaling pathway | regulation of intracellular signal transduction | anatomical structure development | metabolic process | cell-cell junction assembly | regulation of body fluid levels | negative regulation of programmed cell death | positive regulation of lipopolysaccharide-mediated signaling pathway | cell adhesion | protein kinase activity | positive regulation of cellular component biogenesis | organic substance metabolic process | cell death | regulation of endothelial cell proliferation | regulation of cell activation | positive regulation of G-protein coupled receptor protein signaling pathway | positive regulation of ERK1 and ERK2 cascade | positive regulation of cAMP-mediated signaling | regulation of phosphate metabolic process | positive regulation of endothelial cell migration | negative regulation of glial cell apoptotic process | positive regulation of MAPK cascade | anatomical structure formation involved in morphogenesis | regulation of epithelial cell migration | regulation of response to wounding | regulation of cell communication | regulation of blood vessel endothelial cell migration | regulation of macrophage differentiation | signaling | covalent chromatin modification | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | anatomical structure morphogenesis | regulation of developmental process | regulation of G-protein coupled receptor protein signaling pathway | kinase activity | developmental process | organelle organization | cellular protein modification process | histone kinase activity (H3-T6 specific) | tube development | regulation of cell-cell adhesion | positive regulation of metabolic process | chromosome organization | positive regulation of myeloid leukocyte differentiation | cellular metabolic process | regulation of cell death | positive regulation of cell motility | negative regulation of cell death | circulatory system development | positive regulation of angiogenesis | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | cell-cell junction organization | regulation of phosphorus metabolic process

GO Cellular Component

non-motile cilium | intracellular membrane-bounded organelle | neuron projection | ciliary membrane | organelle membrane | cell projection membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | cell projection | endomembrane system | plasma membrane | cilium | photoreceptor outer segment | perinuclear region of cytoplasm | mitochondrion | photoreceptor disc membrane | 9+0 non-motile cilium | photoreceptor cell cilium | membrane-bounded organelle | nucleus | organelle | mitochondrial envelope | cell periphery | mitochondrial membrane | cytosol | intracellular | membrane